{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T15:19:12Z","timestamp":1792423152086,"version":"4.5.0"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T00:00:00Z","timestamp":1679875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Mycoplasma hominis<\/jats:italic> and <jats:italic>Ureaplasma<\/jats:italic> species infections in the post\u2010transplant setting are believed to be donor\u2010derived and can be associated with poor outcomes. Difficulty in culturing and identifying these organisms is a significant barrier to diagnosis and early intervention. Tetracyclines, macrolides and fluoroquinolones are the mainstay treatments to cure these infections; however, there are increasing reports of antibiotic resistance. In this case series, we report our single\u2010centre experience with <jats:italic>M. hominis<\/jats:italic> and <jats:italic>U. urealyticum<\/jats:italic> infection after lung transplantation (9 recipients, all men, mean age 56 years). Delayed diagnosis was common. Young donor age (mean age 23\u00a0yrs) and high\u2010risk donor social history (67%) were repeatedly noted in these cases, and all infections were associated with significant morbidity (anastomosis and sternal wound infection, empyema, mediastinitis, pericarditis). Two patients died; with one directly related to <jats:italic>Ureaplasma urealyticum<\/jats:italic> infection. In conclusion post lung transplant <jats:italic>M. hominis<\/jats:italic>, and <jats:italic>U. urealyticum<\/jats:italic> infections are challenging and carry high morbidity. More prospective studies are required to assess the true prevalence, full spectrum of complications and utility of molecular diagnostics to aid early diagnosis and identify antibiotic susceptibility of <jats:italic>Mycoplasma<\/jats:italic> and <jats:italic>Ureaplasma<\/jats:italic> infections in the post\u2010lung transplant setting.\n<jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/tid14058-gra-0001-m.png\"><jats:alt-text>image<\/jats:alt-text><\/jats:graphic><\/jats:boxed-text><\/jats:p>","DOI":"10.1111\/tid.14058","type":"journal-article","created":{"date-parts":[[2023,3,28]],"date-time":"2023-03-28T06:44:50Z","timestamp":1679985890000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["<i>Mycoplasma hominis<\/i> and <i>Ureaplasma urealyticum<\/i> infections in the immediate post\u2010lung transplant period: A case series and literature review"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9551-8184","authenticated-orcid":false,"given":"Chandima","family":"Divithotewala","sequence":"first","affiliation":[{"name":"Queensland Lung Transplant Service The Prince Charles Hospital  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma L.","family":"Sweeney","sequence":"additional","affiliation":[{"name":"The University of Queensland Centre for Clinical Research Faculty of Medicine, The University of Queensland  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2742-1556","authenticated-orcid":false,"given":"Andrew","family":"Burke","sequence":"additional","affiliation":[{"name":"Queensland Lung Transplant Service The Prince Charles Hospital  Brisbane 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