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An extensive microbiologic and molecular workup was performed, ultimately leading to a diagnosis of donor\u2010derived toxoplasmosis with associated hemophagocytic lymphohistiocytosis in the recipient. This case highlights the potential for post\u2010transplant toxoplasmosis in high\u2010risk mismatch (D+\/R\u2010) recipients, as well as the role of <jats:italic>Toxoplasma<\/jats:italic>\u2010targeted prophylaxis in such patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.14079","type":"journal-article","created":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T13:00:58Z","timestamp":1686142858000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Complex considerations \u2013 Fever and pancytopenia after solid organ transplantation"],"prefix":"10.1111","volume":"25","author":[{"given":"Elena Vald\u00e9s","family":"Franc\u00ed","sequence":"first","affiliation":[{"name":"Nephrology Department Cl\u00ednico San Carlos University Hospital  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth O.","family":"Adekunle","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Medical University of South Carolina  Charleston South Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcio","family":"Nucci","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Federal University of Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie M.","family":"Pouch","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Emory University School of Medicine  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,6]]},"reference":[{"key":"e_1_2_17_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.13732"},{"key":"e_1_2_17_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra064928"},{"key":"e_1_2_17_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.13547"},{"key":"e_1_2_17_5_1","article-title":"Donor\u2010Derived Tuberculosis: A Case Report and the Role of Communication Gaps in Transplantation Safety","volume":"2021","author":"Clemente WT","year":"2021","journal-title":"Case Rep Transplant"},{"key":"e_1_2_17_6_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6630a1"},{"key":"e_1_2_17_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/JBM.S46255"},{"key":"e_1_2_17_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.11368"},{"key":"e_1_2_17_9_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-020117-043625"},{"key":"e_1_2_17_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2018894618"},{"key":"e_1_2_17_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2020.101515"},{"key":"e_1_2_17_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2011.1.178"},{"key":"e_1_2_17_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.14392"},{"key":"e_1_2_17_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000009283"},{"key":"e_1_2_17_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-020-03067-6"},{"key":"e_1_2_17_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir806"},{"key":"e_1_2_17_17_1","unstructured":"UNOS.Guidance regarding donor Toxoplasma screening and organ acceptance.2017. 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