{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T03:41:40Z","timestamp":1785296500840,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T00:00:00Z","timestamp":1698969600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000092","name":"U.S. National Library of Medicine","doi-asserted-by":"publisher","award":["T15LM011271"],"award-info":[{"award-number":["T15LM011271"]}],"id":[{"id":"10.13039\/100000092","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Post\u2010acute sequelae of coronavirus disease 2019 (COVID\u201019) (PASC), defined as prolonged symptoms following an episode of COVID\u201019, is not well\u2010characterized in solid organ transplant recipients (SOTR). In this study, we aimed to assess the prevalence of PASC in SOTR, its descriptive characteristics, and associated risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively identified SOTRs with acute COVID\u201019 between June 1, 2020 and April 15, 2022, and abstracted demographic and medical history, characteristics of acute COVID\u201019 illness, and COVID\u201019 vaccination status. We defined PASC as ongoing\/new symptoms present at 6\u00a0weeks or longer following acute COVID\u201019 diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 208 SOTRs with acute COVID\u201019, 72 (35%) developed PASC. Common symptoms were respiratory symptoms (67%), headache (40%), and difficulty concentrating (10%). Severe acute COVID\u201019 disease and presence of respiratory symptoms were associated with higher odds of PASC in multivariable analyses, while receipt of at least one COVID\u201019 vaccination prior to transplantation was protective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We found that PASC occurs in about a third of SOTRs with acute COVID\u201019 and has similar symptoms as described previously in immunocompetent hosts. Pre\u2010transplant vaccination may be protective. Further prospective multicenter studies are needed.\n<jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/tid14167-gra-0001-m.png\"><jats:alt-text>image<\/jats:alt-text><\/jats:graphic><\/jats:boxed-text><\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.14167","type":"journal-article","created":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T18:11:44Z","timestamp":1699035104000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Post\u2010acute sequelae of COVID\u201019 in solid organ transplant recipients"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8861-1150","authenticated-orcid":false,"given":"Rachel","family":"Sigler","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases The University of Kansas Health System  Kansas City Kansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina","family":"Covarrubias","sequence":"additional","affiliation":[{"name":"Division of Transplant and Hepatobiliary Surgery Department of Surgery University of California, San Diego  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Infectious Disease and Global Public Health Department of Medicine University of California, San Diego  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo Barriola","family":"Rubarth","sequence":"additional","affiliation":[{"name":"Department of Medicine University of California, San Diego  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Torosian","sequence":"additional","affiliation":[{"name":"Department of Medicine University of California, San Diego  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Ramirez","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Division of Transplant and Hepatobiliary Surgery Department of Surgery University of California, San Diego  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Bharti","sequence":"additional","affiliation":[{"name":"Division of Transplant and Hepatobiliary Surgery Department of Surgery University of California, San Diego  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"DeGruttola","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Harvard University School of Public Health  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4051-5629","authenticated-orcid":false,"given":"Saima","family":"Aslam","sequence":"additional","affiliation":[{"name":"Division of Transplant and Hepatobiliary Surgery Department of Surgery University of California, San Diego  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,3]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"CDC.Long COVID or post\u2010COVID conditions.CDC. 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