{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:57:01Z","timestamp":1789261021306,"version":"build-2803163510"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,12,31]],"date-time":"2023-12-31T00:00:00Z","timestamp":1703980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Transplanting lungs from donors with positive blood cultures has not been shown to adversely affect survival. There is limited evidence for potential effects on other outcomes, such as hospital course, graft function, and transmission of infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective cohort study included adult patients who underwent lung\u2010only transplantation for the first time between March 2010 and December 2022. Outcomes of patients whose donors had positive blood cultures within 72\u00a0h of transplant were compared to patients whose donors had negative blood cultures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010five (10.8%) of 232 donors had positive blood cultures, including a single, unexpected case with candidemia. The most commonly isolated bacteria were <jats:italic>Enterobacter cloacae<\/jats:italic> (<jats:italic>n<\/jats:italic>\u00a0=\u00a05), <jats:italic>Klebsiella pneumoniae<\/jats:italic> (<jats:italic>n<\/jats:italic>\u00a0=\u00a05), <jats:italic>Acinetobacter baumannii<\/jats:italic> (<jats:italic>n<\/jats:italic>\u00a0=\u00a03), <jats:italic>Pseudomonas aeruginosa<\/jats:italic> (<jats:italic>n<\/jats:italic>\u00a0=\u00a03), and <jats:italic>Staphylococcus aureus<\/jats:italic> (<jats:italic>n<\/jats:italic>\u00a0=\u00a03). Eleven donors had identical bacteria in their respiratory cultures. All patients who were transplanted from donors with positive blood cultures survived beyond 90 days. Positive donor blood cultures were not associated with longer hospital stay, in\u2010hospital complications, acute cellular rejection, or the achievement of 80% predicted forced expiratory volume in the first second. Probable transmission of donor bacteremia occurred in only two cases (both with <jats:italic>S. aureus<\/jats:italic>). These two donors had positive respiratory cultures with the same organism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The study did not find an increased risk of adverse events when transplanting lungs from donors with positive blood cultures. Allograft cultures may be more predictive of the risk of transmitting infections.\n<jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/tid14224-gra-0001-m.png\"><jats:alt-text>image<\/jats:alt-text><\/jats:graphic><\/jats:boxed-text><\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.14224","type":"journal-article","created":{"date-parts":[[2023,12,31]],"date-time":"2023-12-31T11:49:36Z","timestamp":1704023376000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Donor blood cultures and outcomes after lung transplantation: a single\u2010center 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