{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T01:13:16Z","timestamp":1792199596068,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T00:00:00Z","timestamp":1721088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T00:00:00Z","timestamp":1721088000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100012399","name":"Biomedical Advanced Research and Development Authority","doi-asserted-by":"publisher","award":["75A50122C00022"],"award-info":[{"award-number":["75A50122C00022"]}],"id":[{"id":"10.13039\/100012399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2024,10]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Five organs (heart, right lung, liver, right, and left kidneys) from a deceased patient were transplanted into five recipients in four US states; the deceased patient was identified as part of a healthcare\u2010associated fungal meningitis outbreak among patients who underwent epidural anesthesia in Matamoros, Mexico.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n After transplant surgeries occurred,\n Fusarium solani<\/jats:italic>\n species complex, a fungal pathogen with a high case\u2010mortality rate, was identified in cerebrospinal fluid from the organ donor by metagenomic next\u2010generation sequencing (mNGS) and fungal\u2010specific polymerase chain reaction and in plasma by mNGS.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Four of five transplant recipients received recommended voriconazole prophylaxis; four were monitored weekly by serum (1\u20103)\u2010\u03b2\u2010\n d<\/jats:sc>\n \u2010glucan testing. All five were monitored for signs of infection for at least 3 months following transplantation. The liver recipient had graft failure, which was attributed to an etiology unrelated to fungal infection. No fungal DNA was identified in sections of the explanted liver, suggesting that\n F. solani<\/jats:italic>\n species complex did not contribute to graft failure. The remaining recipients experienced no signs or symptoms suggestive of fusariosis.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Antifungal prophylaxis may be useful in preventing donor\u2010derived infections in recipients of organs from donors that are found to have\n Fusarium<\/jats:italic>\n meningitis.\n \n \n image<\/jats:alt-text>\n <\/jats:graphic>\n <\/jats:boxed-text>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/tid.14331","type":"journal-article","created":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T11:42:53Z","timestamp":1721130173000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Outcomes in solid organ transplant recipients receiving organs from a donor with\n Fusarium solani<\/i>\n species complex meningitis"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4113-8412","authenticated-orcid":false,"given":"Isabel S.","family":"Griffin","sequence":"first","affiliation":[{"name":"Division of Healthcare Quality Promotion National Center for Emerging and Zoonotic Infectious Diseases Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5707-528X","authenticated-orcid":false,"given":"Dallas J.","family":"Smith","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5564-8785","authenticated-orcid":false,"given":"Pallavi","family":"Annambhotla","sequence":"additional","affiliation":[{"name":"Division of Healthcare Quality Promotion National Center for Emerging and Zoonotic Infectious Diseases Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5054-7616","authenticated-orcid":false,"given":"Jeremy A. W.","family":"Gold","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4784-7589","authenticated-orcid":false,"given":"Luis","family":"Ostrosky\u2010Zeichner","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases McGovern Medical School Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol A.","family":"Kauffman","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases University of Michigan Medical School Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9264-9952","authenticated-orcid":false,"given":"Lalitha","family":"Gade","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1086-8041","authenticated-orcid":false,"given":"Anastasia","family":"Litvintseva","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3442-7454","authenticated-orcid":false,"given":"Daniel ZP","family":"Friedman","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases and Global Health University of Chicago Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1326-3013","authenticated-orcid":false,"given":"Angie G","family":"Nishio Lucar","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Virginia Health System Charlottesville Virginia 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