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We conducted a narrative review of the literature on HHV\u20108 in transplantation with a goal of illuminating the spectrum of HHV\u20108\u2010associated diseases in this vulnerable population, modes of disease transmission, and the potential role for donor and recipient screening.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>HHV\u20108\u2010associated KS, primary effusion lymphoma (PEL), multicentric Castleman disease (MCD), and KSHV inflammatory cytokine disorder (KICS) may affect transplant recipients; with the exception of KS, these conditions are rare but carry high morbidity and mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>HHV\u20108\u2010associated diseases have diverse and protean manifestations in transplant recipients, with potentially fatal outcomes. HHV\u20108 seroprevalence among organ donors and the magnitude of risk for donor\u2010derived HHV\u20108 infection or clinically significant disease remain unknown and require further study.\n<jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/tid14334-gra-0001-m.png\"><jats:alt-text>image<\/jats:alt-text><\/jats:graphic><\/jats:boxed-text><\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.14334","type":"journal-article","created":{"date-parts":[[2024,7,7]],"date-time":"2024-07-07T10:09:17Z","timestamp":1720346957000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["HHV\u20108\u2010associated diseases in transplantation: A case report and narrative review focused on diagnosis and 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