{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T23:07:03Z","timestamp":1784588823350,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T00:00:00Z","timestamp":1721088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T00:00:00Z","timestamp":1721088000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>Human herpesviruses (HHVs) cause a wide variety of central nervous system (CNS) infections including meningitis and encephalitis. While HHV\u20108 is not typically associated with neurological diseases, several studies have indicated a relationship, such as secondary central nervous system (CNS) metastases and a few isolated cases of HHV\u20108 encephalitis in acquired immunodeficiency syndrome (HIV). However, it has not been previously linked to encephalitis in solid organ transplantation (SOT). This case presents the first\u2010ever instance of HHV\u20108 encephalitis in a SOT recipient. Our case highlights the association of HHV\u20108\u2010related diseases, such as post\u2010transplant Kaposi's Sarcoma (KS), with encephalitis. The patient was diagnosed with KS before developing neurological symptoms and received a prompt clinical response through intravenous foscarnet and ganciclovir treatment for 14 days. It is important to note that HHV\u20108 is a rare cause of encephalitis, and diagnosis requires a high index of suspicion in the appropriate clinical context, allowing for the use of antiviral therapy. This case also underscores the importance of considering the possibility of HHV\u20108\u2010related diseases in SOT recipients, as they are at risk of developing such infections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/tid.14343","type":"journal-article","created":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T11:32:00Z","timestamp":1721129520000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Emerging shadows: HHV\u20108\u2010associated encephalitis unveiled in a solid organ transplant recipient"],"prefix":"10.1111","volume":"26","author":[{"given":"Inderjit","family":"Mann","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Infection Control and Employee Health, University of Texas MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar","family":"Morado\u2010Aramburo","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases UT Health McGovern Medical School  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4155-7089","authenticated-orcid":false,"given":"Rodrigo","family":"Hasbun","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases UT Health McGovern Medical School  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,16]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200005150-00003"},{"issue":"7","key":"e_1_2_3_3_1","first-page":"2826","article-title":"Risk of Kaposi's sarcoma\u2010associated herpes virus transmission from donor allografts among Italian posttransplant Kaposi's sarcoma patients","volume":"90","author":"Parravicini C","year":"1997","journal-title":"Blood"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379\u2010019\u20100365\u2010y"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood\u20102012\u201004\u2010421412"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14346"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.dmih2\u20100007\u20102015"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12225"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20106143.2012.04290.x"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041\u20101345(98)00550\u20108"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.01844\u201015"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiw545"},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1086\/509330"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002030\u2010199709000\u201000006"},{"key":"e_1_2_3_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200011093431905"},{"key":"e_1_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199711000-00006"},{"key":"e_1_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200207150-00023"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.14343","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tid.14343","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tid.14343","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T07:14:52Z","timestamp":1773645292000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tid.14343"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,16]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1111\/tid.14343"],"URL":"https:\/\/doi.org\/10.1111\/tid.14343","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,16]]},"assertion":[{"value":"2024-06-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14343"}}