{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T07:30:30Z","timestamp":1788420630239,"version":"build-2803163510"},"reference-count":209,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T00:00:00Z","timestamp":1730678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016221","name":"Rowan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016221","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Arthropod\u2010borne flaviviruses (ABFs), transmitted by mosquitoes or ticks, are increasing due to climate change and globalization. This scoping review examines the epidemiology, clinical characteristics, diagnostics, treatment, and outcomes of ABF infection in solid organ transplant recipients (SOTRs). A database search up to January 25, 2024, focused on ABFs such as West Nile virus (WNV), dengue virus (DENV), Japanese encephalitis virus (JEV), Powassan virus (POWV), yellow fever virus (YFV), and Zika virus (ZIKV), limited to SOTRs.<\/jats:p>\n                  <jats:p>We identified 173 WNV cases from 84 studies, with 28 donor\u2010derived infections (DDIs). Common clinical features included fever (78.5%), altered mental status (65.1%), and weakness or paralysis (45.6%). Treatment involved reducing immunosuppression (IS) in 93 cases, with intravenous immunoglobulin (IVIG), interferon alfa\u20102b, and ribavirin used in 75 cases. Seven cases involved graft loss or rejection post\u2010infection. WNV infection had a 23.7% mortality rate, with severe neurological complications in 43.9%<\/jats:p>\n                  <jats:p>For DENV infection, 386 cases from 47 studies were identified, including 14 DDI cases. Symptoms included fever (85%), myalgias (56.4%), and headache or retro\u2010orbital pain (34.6%). Severe dengue occurred in 50 cases (13.0%). IVIG was administered in six cases. Reduction in IS was reported in 116 patients. DENV mortality rate was 4.9%.<\/jats:p>\n                  <jats:p>Additionally, 26 cases of less common ABFs such as JEV, POWV, YFV, and ZIKV were described.<\/jats:p>\n                  <jats:p>\n                    In summary, ABF infections among SOTRs are associated with higher morbidity and mortality compared to the general population, emphasizing the need for improved preventive strategies, timely diagnosis, and optimized management protocols.\n                    <jats:boxed-text content-type=\"graphic\" position=\"anchor\">\n                      <jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/tid14400-gra-0001-m.png\">\n                        <jats:alt-text>image<\/jats:alt-text>\n                      <\/jats:graphic>\n                    <\/jats:boxed-text>\n                  <\/jats:p>","DOI":"10.1111\/tid.14400","type":"journal-article","created":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T07:09:24Z","timestamp":1730704164000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A Scoping Review of Arthropod\u2010Borne Flavivirus Infections in Solid Organ Transplant Recipients"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1578-1482","authenticated-orcid":false,"given":"Seohyeon","family":"Im","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Mass General Brigham\u2010Salem Hospital  Salem Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fadie","family":"Altuame","sequence":"additional","affiliation":[{"name":"Department of Neurology Brigham and Women's Hospital  Boston Massachusetts USA"},{"name":"Department of Neurology Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel H.","family":"Gonzalez\u2010Bocco","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Brigham and Women's Hospital  Boston Massachusetts USA"},{"name":"Department of Medical Oncology Dana\u2010Farber Cancer Institute  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cilomar","family":"Martins de Oliveira Filho","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Mass General Brigham\u2010Salem Hospital  Salem Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Goldstein","family":"Shipper","sequence":"additional","affiliation":[{"name":"Cooper Medical School of Rowan University  Camden New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5720-9994","authenticated-orcid":false,"given":"Maricar","family":"Malinis","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Infectious Diseases Vanderbilt University School of Medicine  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2698-981X","authenticated-orcid":false,"given":"Carlo","family":"Foppiano Palacios","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Infectious Diseases Cooper Medical School of Rowan University  Camden New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978\u20100\u201012\u2010408116\u20101.00004\u20105"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2016.11.020"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2020.05.001"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.34172\/hpp.2021.48"},{"key":"e_1_2_8_6_1","unstructured":"Pan American Health Organization.Dengue. 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