{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T11:06:17Z","timestamp":1785323177119,"version":"3.55.0"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T00:00:00Z","timestamp":1736467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2025,3]]},"abstract":"ABSTRACT<\/jats:title>\n \n Introduction<\/jats:title>\n Infections significantly impact morbidity and mortality in lung transplant (LuTx) recipients. This survey focused on documenting current practices regarding the prevention and management of infections in LuTx in Italy.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A 52\u2010question survey was administered online in the period from December 1, 2023, to January 31, 2024, assessing center characteristics, Tx team organization, microbiological investigations, infection prevention, and management. All Italian LuTx centers were invited to participate.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Nine out of 10 Italian LuTx centers answered. Most centers (6\/9, 67%) performed LuTx only on adults.<\/jats:p>\n \n Chronic infection or colonization by\n Mycobacterium abscessus<\/jats:italic>\n and\n Burkholderia cenocepacia<\/jats:italic>\n is considered a contraindication to LuTx in five and two centers, respectively.\n <\/jats:p>\n For cytomegalovirus D+\/R\u2010 patients, prophylaxis is used in six centers (67%), with a variable duration from 3 to 12 months. Two centers also use IgG. Three centers (33%) use a pre\u2010emptive strategy. Four centers (45%) screen for Human herpesvirus 8 infection.<\/jats:p>\n Regarding antibiotic prophylaxis, most centers (6\/9, 67%) utilise a dual regimen of anti\u2010pseudomonal penicillin plus glycopeptide. The two most common durations of antibiotic prophylaxis were 72 h and 7 days, each reported by two centers (22%).<\/jats:p>\n Targeted prophylaxis against fungal infections is employed by a minority of centers (4\/9, 44%). Inhaled amphotericin B is the most common antifungal, used as targeted prophylaxis (2\/4, 50%) and universal prophylaxis (2\/5, 40%).<\/jats:p>\n Almost all centers (8\/9, 89%) involve the Tx infectious diseases specialist in the recipient management since the pre\u2010listing period.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n There is considerable heterogeneity in infection management among Italian LuTx centers. Establishing a shared platform for data collection and outcome evaluation is essential to improve infection management.\n \n \n image<\/jats:alt-text>\n <\/jats:graphic>\n <\/jats:boxed-text>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/tid.14413","type":"journal-article","created":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T08:08:58Z","timestamp":1736496538000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Infections Management in the Lung Transplant Setting in Italy: A Web\u2010Survey"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0383-9579","authenticated-orcid":false,"given":"Andrea","family":"Lombardi","sequence":"first","affiliation":[{"name":"Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico Infectious Diseases Unit Milano Italy"},{"name":"Department of Pathophysiology and Transplantation University of Milan Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2883-5061","authenticated-orcid":false,"given":"Paolo","family":"Grossi","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery, Infectious and Tropical Diseases Unit University of Insubria\u2010ASST\u2010Sette Laghi Varese Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malgorzata","family":"Mikulska","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Division of Infectious Diseases University of Genova Genova Italy"},{"name":"IRCCS Ospedale Policlinico San Martino Genova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8273-7601","authenticated-orcid":false,"given":"Maddalena","family":"Giannella","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences Alma Mater Studiorum University of Bologna Bologna Italy"},{"name":"Infectious Diseases Unit IRCCS Azienda Ospedaliero\u2010Universitaria di Bologna Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato","family":"Pascale","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences Alma Mater Studiorum University of Bologna Bologna Italy"},{"name":"Infectious Diseases Unit IRCCS Azienda Ospedaliero\u2010Universitaria di Bologna Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serena","family":"Marinello","sequence":"additional","affiliation":[{"name":"Infectious and Tropical Diseases Unit Padova University Hospital Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Montagnani","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Infectious and Tropical Diseases Unit Azienda Ospedaliero\u2010Universitaria Senese Siena Italy"},{"name":"Department of Medical Biotechnologies University of Siena Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5246-928X","authenticated-orcid":false,"given":"Elena","family":"Seminari","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico IRCCS San Matteo Infectious and Tropical Diseases Unit Pavia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Corcione","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Infectious Diseases University of Torino Torino Italy"},{"name":"Department of Infectious Diseases Tufts University School of Medicine Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Bandera","sequence":"additional","affiliation":[{"name":"Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico Infectious Diseases Unit Milano Italy"},{"name":"Department of Pathophysiology and Transplantation University of Milan Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Bertani","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery and Lung Transplantation, Chest Center ISMETT\u2010IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione Palermo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8612-5581","authenticated-orcid":false,"given":"Alessandra","family":"Mularoni","sequence":"additional","affiliation":[{"name":"Unit of Infectious Diseases and Infection Control ISMETT\u2010IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione Palermo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the Infection Prevention and Treatment Working Group of the LUNG\u2010SITO study 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