{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T13:13:46Z","timestamp":1784121226451,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Vancomycin\u2010resistant enterococci (VRE) are multidrug\u2010resistant microorganisms (MDRO) commonly isolated in liver transplant recipients and potentially associated with worse outcomes. We aimed to identify risk factors associated with VRE colonization in liver transplantation (LT) and its impact on posttransplant survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a retrospective cohort that included all adults who underwent LT between 2010 and 2022 at a tertiary\u2010level hospital in S\u00e3o Paulo, Brazil. Multivariate analyses were performed using logistic regression for VRE colonization risk and Cox regression for 180\u2010day survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 1209 patients were included, 119 patients (9.8%) were colonized with VRE at LT, while 175 (14.5%) were colonized after LT, 77 (6.4%) patients developed VRE infection after LT. In the multivariate analysis, use of SBP prophylaxis, presence of acute\u2010on\u2010chronic liver failure, hepatitis B virus infection, ASA score, length of hospital stay and MELD score were all associated with VRE colonization before LT. For VRE colonization after LT, the predictors were length of hospital stay before LT, MELD score, carbapenem\u2010resistant Gram\u2010negative colonization, intraoperative bleeding and re\u2010transplantation. Note that 180\u2010day mortality rate among VRE colonization and infection was, respectively, 33.6% and 50.6% compared to 17.8% of non\u2010colonized patients, and this difference was not statistically significant after adjustment for confounders in multivariate analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>VRE colonization or infection had no impact on survival in a large cohort of liver transplantrecipients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/tid.70072","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T12:50:26Z","timestamp":1753188626000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Colonization by Vancomycin\u2010Resistant Enterococci in Liver Transplantation: Risk Factors and Survival Impact"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7525-3238","authenticated-orcid":false,"given":"Nathalia Neves","family":"Nunes","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Hospital das Clinicas, Universidade de S\u00e3o Paulo S\u00e3o Paulo Brazil"},{"name":"Faculdade de Medicina de Itajub\u00e1 Itajub\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lohayne Alves","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Hospital das Clinicas, Universidade de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Spad\u00e3o","sequence":"additional","affiliation":[{"name":"Working Committee for Hospital Epidemiology and Infection Control Hospital das Clinicas, Universidade de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6992-9326","authenticated-orcid":false,"given":"Alice Tung Wan","family":"Song","sequence":"additional","affiliation":[{"name":"Division of Liver and Gastrointestinal Transplant Department of Surgery Hospital das Clinicas, Universidade de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debora Raquel Benedita","family":"Terrabuio","sequence":"additional","affiliation":[{"name":"Division of Liver and Gastrointestinal Transplant Department of Surgery Hospital das Clinicas, Universidade de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Augusto Carneiro","family":"D'Albuquerque","sequence":"additional","affiliation":[{"name":"Division of Liver and Gastrointestinal Transplant Department of Surgery Hospital das Clinicas, Universidade de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edson","family":"Abdala","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Hospital das Clinicas, Universidade de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maristela Pinheiro","family":"Freire","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Hospital das Clinicas, Universidade de S\u00e3o Paulo S\u00e3o Paulo Brazil"},{"name":"Working Committee for Hospital Epidemiology and Infection Control Hospital das Clinicas, Universidade de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.15403\/jgld\u20103616"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i20.6201"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2011.12.005"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12784"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2019.04.014"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12690"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0245091"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20100012.2005.00362.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13756\u2010020\u20100683\u20103"},{"key":"e_1_2_10_11_1","volume-title":"Analysis and Presentation of Cumulative Antimicrobial Susceptibility Test Data","author":"Hindler J. 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