{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:28:31Z","timestamp":1790090911375,"version":"4.0.1"},"reference-count":23,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>People who have received kidney transplants (KTs) are at increased risk for herpes zoster (HZ). The recombinant zoster vaccine (RZV) is recommended for immunocompromised individuals based on immunogenicity data, including studies in solid organ transplant populations. However, evidence on its real\u2010world effectiveness in transplant recipients remains limited. In South Korea, RZV became available in March 2023, providing an opportunity to assess the association between RZV vaccination and incident HZ among individuals who received KT in a retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included all adults (\u2265 18 years) who underwent KT at a single 2700\u2010bed tertiary center in Seoul, South Korea, from January 2020 through December 2024. Vaccination status was treated as a time\u2010varying exposure. Incidence rates and adjusted hazard ratios (aHRs) were estimated using time\u2010dependent Cox regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 1761 adults who received KT, 388 individuals received the RZV, while 1373 remained unvaccinated. During follow\u2010up, HZ occurred in 78 unvaccinated individuals (5.7%), while no cases occurred in the vaccinated group over 398.3 person\u2010years. The incidence rate of HZ was 16.4 per 1000 person\u2010years (95% confidence interval [CI]: 13.0\u201320.5) in the unvaccinated group and 0 (95% CI: 0.0\u20139.3) in the vaccinated group. In a time\u2010dependent Cox model with Firth penalization, RZV was associated with a lower hazard of HZ (aHR, 0.06; 95% CI: 0.00\u20130.43;\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      No HZ events occurred among vaccinated individuals in this cohort, a finding consistent with a protective association of RZV after KT. These findings support current recommendations for RZV use in immunocompromised populations.\n                      <jats:boxed-text content-type=\"graphic\" position=\"anchor\">\n                        <jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/tid70300-gra-0001-m.png\">\n                          <jats:alt-text>image<\/jats:alt-text>\n                        <\/jats:graphic>\n                      <\/jats:boxed-text>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/tid.70300","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T11:27:01Z","timestamp":1786534021000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Effectiveness of the Recombinant Zoster Vaccine for Preventing Herpes Zoster in Individuals With Kidney Transplants: A Retrospective Cohort Study"],"prefix":"10.1111","author":[{"given":"Kyungsup","family":"Kwon","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So Yun","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7417-0318","authenticated-orcid":false,"given":"Euijin","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seongman","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5018-5304","authenticated-orcid":false,"given":"Hyunwook","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Kidney and Pancreas Transplantation Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiwon","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Jae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Kidney and Pancreas Transplantation Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Pil","family":"Chong","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Hoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Kidney and Pancreas Transplantation Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang\u2010Ho","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang\u2010Oh","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung\u2010Han","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of 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