{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T12:30:24Z","timestamp":1786537824003,"version":"build-2736575974"},"reference-count":35,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transplant Infectious Dis"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Kidney transplantation from living donors (LDs) offers benefits over donation after brain death (DBD). Whether LD independently protects against infection incidence remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We compared posttransplant infection between LD (\n                      <jats:italic>n<\/jats:italic>\n                      = 102) and DBD (\n                      <jats:italic>n<\/jats:italic>\n                      = 401) groups in a prospective observational cohort of 503 KT recipients at a tertiary\u2010care center. Crude and adjusted associations between donor type and infection risk were assessed using propensity score (PS) modeling and multivariable Cox regression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Cumulative incidence rates of overall and bacterial infection were 58.6% and 43.7%, respectively. Compared to DBD recipients, LD patients had lower crude risks for overall (hazard ratio [HR]:\u00a00.53; 95% confidence interval [CI]: 0.39\u20130.74;\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value &lt; 0.001) and bacterial infection (HR:\u00a00.59; 95% CI: 0.41\u20130.87;\u00a0\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value = 0.007). In PS\u2010based models, donor type was no longer significant for overall (PS\u2010adjusted HR: 0.78; 95% CI: 0.52\u20131.18;\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value = 0.244) or bacterial infection (PS\u2010adjusted HR: 0.94, 95% CI: 0.59\u20131.50;\u00a0\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value = 0.802). Similar effect modification appeared for secondary outcomes and adjusted multivariable models.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Donor type did not independently influence posttransplant infection risk after adjustment for baseline recipient factors. Lower infection incidence in LD recipients may reflect favorable recipient\u2010 and transplant\u2010related characteristics rather than donor\u2010specific factors.\n                      <jats:boxed-text content-type=\"graphic\" position=\"anchor\">\n                        <jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/tid70301-gra-0001-m.png\">\n                          <jats:alt-text>image<\/jats:alt-text>\n                        <\/jats:graphic>\n                      <\/jats:boxed-text>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/tid.70301","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T11:38:51Z","timestamp":1786534731000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Infectious Complications in Living Donation Versus Donation After Brain Death Kidney Transplantation"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2150-5748","authenticated-orcid":false,"given":"Isabel","family":"Rodr\u00edguez\u2010Goncer","sequence":"first","affiliation":[{"name":"Unit of Infectious Diseases Instituto De Investigaci\u00f3n Sanitaria Hospital \u201c12 De Octubre\u201d (imas12) University Hospital \u201c12 De Octubre\u201d  Madrid Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Infecciosas (CIBERINFEC) Instituto De Salud Carlos III (ISCIII)  Madrid Spain"},{"name":"School of Medicine Universidad Complutense  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6534-2691","authenticated-orcid":false,"given":"Gabriel","family":"Motoa","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division Transplant and Immunocompromised Host Service Massachusetts General Hospital Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Nephrology Instituto De Investigaci\u00f3n Sanitaria Hospital \u201c12 De Octubre\u201d (imas12) Hospital Universitario \u201c12 De Octubre\u201d  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5333-7529","authenticated-orcid":false,"given":"Francisco","family":"L\u00f3pez\u2010Medrano","sequence":"additional","affiliation":[{"name":"Unit of Infectious Diseases Instituto De Investigaci\u00f3n Sanitaria Hospital \u201c12 De Octubre\u201d (imas12) University Hospital \u201c12 De Octubre\u201d  Madrid Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Infecciosas (CIBERINFEC) Instituto De Salud Carlos III (ISCIII)  Madrid Spain"},{"name":"School of Medicine Universidad Complutense  Madrid 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