{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T19:14:38Z","timestamp":1783970078784,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,7,5]],"date-time":"2013-07-05T00:00:00Z","timestamp":1372982400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:sec><jats:title>Aim\/Objectives<\/jats:title><jats:p>To access the incidence and specificity of maternal red blood cells alloimmunisation and its relevant clinical impact in Greece.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>The rate of alloimmunisation in pregnant women in Greece is unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials\/Methods<\/jats:title><jats:p>We performed a 4\u2010year study in two tertiary hospitals in Greece. Demographics, transfusion and obstetric history were analysed. Maternal alloimmunisation was detected with indirect anti\u2010globulin test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We investigated 4368 pregnant women. Of which 3292 (75\u00b737%) were Greek and 1076 (24\u00b763%) were migrants. In 39 alloimmunised women, 41 alloantibodies were detected (0\u00b789%). The incidence of alloimmunisation was 0\u00b766% (22\/3292) in Greeks and 1\u00b776% (17\/1076) in migrants (<jats:italic>P<\/jats:italic>\u2009=\u20090\u00b701). Anti\u2010D was the most frequent alloantibody (0\u00b718%). Anti\u2010D was more frequent in migrants; 5\u00b776% compared to 0\u00b756% in Greek <jats:styled-content style=\"fixed-case\">RhD<\/jats:styled-content> negative women (<jats:italic>P<\/jats:italic>\u2009=\u20090\u00b7002).<\/jats:p><jats:p>Other antibody specificities in declining frequency rank were anti\u2010K, anti\u2010E, anti\u2010Lea, anti\u2010M, anti\u2010c, anti\u2010Ce, anti\u2010Jka, anti\u2010Jkb and anti\u2010C.<\/jats:p><jats:p>Primiparae vs para &gt;2 and past history of blood transfusion were significantly associated with alloimmunisation during pregnancy (<jats:italic>P<\/jats:italic>\u2009=\u20090\u00b70088, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090\u00b70001, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our results depict differences in the delivery of health care between migrants and Greek women, as well as the heterogeneity in practices for the prevention of haemolytic disease of foetus and newborn in Greece and highlight the need for the implementation of nationwide guidelines.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tme.12063","type":"journal-article","created":{"date-parts":[[2013,7,5]],"date-time":"2013-07-05T10:00:23Z","timestamp":1373018423000},"page":"254-259","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Alloimmunisation during pregnancy in Greece: need for nationwide <scp>HDFN<\/scp> prevention programme"],"prefix":"10.1111","volume":"23","author":[{"given":"L.","family":"Foudoulaki\u2010Paparizos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Valsami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Bournas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Tsantes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Grapsas","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology Department General Hospital of Nikea Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Mantzios","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Travlou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Politou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767050601123317"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2010.03006.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3148.2011.01106.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00476-6"},{"key":"e_1_2_7_6_1","first-page":"328","article-title":"Current status of immunoprophylaxis with anti\u2010D immunoglobin","volume":"85","author":"Engelfriet C.P.","year":"2003","journal-title":"Vox Sanguinis"},{"key":"e_1_2_7_7_1","unstructured":"European Union Agency for Fundamental Rights (FRA)(2011) Migrants in an irregular situation: access to healthcare in 10 European Union Member States (ed Union L.P.O.o.t.E.) 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