{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T19:52:04Z","timestamp":1790279524464,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,1,28]],"date-time":"2019-01-28T00:00:00Z","timestamp":1548633600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims\/Objectives<\/jats:title><jats:p>Here, we describe the annual review of the UK blood services' infection surveillance schemes for 2017 (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.gov.uk\/government\/publications\/safe-supplies-annual-review\">www.gov.uk\/government\/publications\/safe\u2010supplies\u2010annual\u2010review<\/jats:ext-link>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>The joint NHS Blood and Transplant\/Public Health England Epidemiology Unit was set up in 1995 to ensure that blood and tissue safety is maintained, inform donor selection and testing policy and add to public health knowledge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Several surveillance schemes for blood, tissues and bacterial screening collect the numbers of donations tested, reactive and confirmed positive in order to monitor trends in infection rates in donors and calculate residual risk of infection. Investigations of potential transfusion transmissions in recipients are also monitored.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the UK in 2017, the risk of testing not detecting a potentially infectious hepatitis B virus or hepatitis C virus or HIV donation was estimated as less than one in two million donations. One hepatitis A virus and one hepatitis E virus transmission incidents were proven to be transfusion\u2010transmitted by unscreened donations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The Safe Supplies annual review provides a clear picture of the very low risk associated with blood and tissues in the UK nowadays. In November 2017, the blood services for England, Wales and Scotland implemented recommendations to reduce the deferrals for higher risk sexual behaviour from 12 to 3 months. The surveillance schemes are adapted to remain fit for purpose as testing and donor selection change.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tme.12576","type":"journal-article","created":{"date-parts":[[2019,1,28]],"date-time":"2019-01-28T20:37:30Z","timestamp":1548707850000},"page":"239-246","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Safe supplies: few infections in UK blood and tissue donors"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3452-0832","authenticated-orcid":false,"given":"C.","family":"Reynolds","sequence":"first","affiliation":[{"name":"NHS Blood and Transplant\/Public Health England Epidemiology Unit NHS Blood and Transplant  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. L.","family":"Davison","sequence":"additional","affiliation":[{"name":"NHSBT\/ PHE Epidemiology Unit, Blood Safety, Hepatitis Sexually Transmitted Infections (STI) and HIV Division Public Health England  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. R.","family":"Brailsford","sequence":"additional","affiliation":[{"name":"NHS Blood and Transplant\/Public Health England Epidemiology Unit NHS Blood and Transplant  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,1,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2010.01412.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12225"},{"key":"e_1_2_7_4_1","first-page":"12670","article-title":"Failure of bacterial screening to detect  Staphylococcus aureus: the English experience of donor follow\u2010up","volume":"24","author":"Brailsford S.R.","year":"2018","journal-title":"Vox Sanguinis"},{"key":"e_1_2_7_5_1","first-page":"46","article-title":"Recruiting individuals into the HTLV cohort study in the United Kingdom: clinical findings and challenges in the first six years, 2003 to 2009","volume":"16","author":"Brant L.J.","year":"2011","journal-title":"Euro Surveillance"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2008.01104.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12135"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12024"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12236"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2017.22.16.30514"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0033328"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurpub\/ckr083"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61034-5"},{"key":"e_1_2_7_14_1","unstructured":"Joint UK Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee(2017a)Change Notification UK National Blood Services No. 15\u20132017 2018.https:\/\/www.transfusionguidelines.org\/document\u2010library\/change\u2010notifications\/change\u2010notifications\u2010issues\u2010in\u20102017(Accessed 17\/7\/18)."},{"key":"e_1_2_7_15_1","unstructured":"Joint UK Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee(2017b)Change Notification UK National Blood Services No. 25\u20132017 Chikungunya Virus.https:\/\/www.transfusionguidelines.org\/document\u2010library\/change\u2010notifications\/change\u2010notifications\u2010issues\u2010in\u20102017(Accessed 17\/7\/18)."},{"key":"e_1_2_7_16_1","unstructured":"Joint UK Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee(2018)The Estimated Residual Risk that a Donation Made in the Infectious Window Period is not Detected on Testing: Risks Specific for HBV HCV and HIV in the UK 2015\u20132017.https:\/\/www.transfusionguidelines.org\/document\u2010library\/position\u2010statements(Accessed 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2017","volume":"12","author":"Public Health England","year":"2018","journal-title":"Health Protection Report"},{"key":"e_1_2_7_24_1","volume-title":"Emerging Infections: Monthly Summaries","author":"Public Health England","year":"2018"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12268"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12638"},{"key":"e_1_2_7_27_1","unstructured":"Safety of Blood Tissues and Organs(2017)Advisory Committee on the Safety of Blood Tissues and Organs (SaBTO): Donor Selection Criteria Report (2017).https:\/\/www.gov.uk\/government\/publications\/blood\u2010tissue\u2010and\u2010cell\u2010donor\u2010selection\u2010criteria\u2010report\u20102017(Accessed 17\/7\/18)."},{"key":"e_1_2_7_28_1","unstructured":"Safety of Blood Tissues and Organs(2018)Protecting patients from getting hepatitis E through transfusion or 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