{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T20:49:27Z","timestamp":1767991767050,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,10,5]],"date-time":"2021-10-05T00:00:00Z","timestamp":1633392000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To retrospectively analyse and report the utilisation of red blood cell (RBC) transfusion in a tertiary otolaryngology, head and neck centre in the United Kingdom.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Twenty\u2010seven per cent of RBC transfusions were for surgical indications in a 2014 England and North Wales survey. Currently, there is limited literature on RBC transfusions in Otolaryngology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods\/materials<\/jats:title><jats:p>All inpatients admitted primarily under the care of the Otolaryngology, Head and Neck service between January 2015 and December 2019 were analysed. The primary outcomes of interest were number of units of RBC transfused over 5\u2009years and distribution across clinical indications. Secondary outcome measure was cost of RBC transfusions over the same time period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Most patients receiving transfusions are aged in their sixth and seventh decades. Epistaxis patients utilised 105 RBC units over the 5\u2009years (56% of total RBC units) with emergency epistaxis accounting for 78% of use. Post\u2010operative Head &amp; Neck Cancer surgery with and without reconstruction required 47 RBC units over 5\u2009years (25% of total RBC units). The mean cost incurred by the department over the 5\u2010year period was \u00a36171.49 (SD 1460.25). The cost has fallen by over \u00a32000 over the 5\u2010year period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Blood transfusion use has fluctuated over the last 5\u2009years. Epistaxis and post\u2010operative Head and Neck cancer cases account for significant use compared with other patient groups. Prehabilitation strategies will add value towards mitigating future consumption of RBC.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tme.12822","type":"journal-article","created":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T02:34:50Z","timestamp":1633574090000},"page":"431-438","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Blood transfusion demands in a tertiary otolaryngology, head and neck centre: A 5\u2010year retrospective cohort study"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4435-4970","authenticated-orcid":false,"given":"Louis","family":"Luke","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Head &amp; Neck Surgery, Addenbrooke's Hospital Cambridge University Hospitals NHS Foundation Trust Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charindu K. I.","family":"Ranmuthu","sequence":"additional","affiliation":[{"name":"Addenbrooke's Hospital University of Cambridge School of Clinical Medicine Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chanuka D. S.","family":"Ranmuthu","sequence":"additional","affiliation":[{"name":"Addenbrooke's Hospital University of Cambridge School of Clinical Medicine Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Habeeb","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head &amp; Neck Surgery, Addenbrooke's Hospital Cambridge University Hospitals NHS Foundation Trust Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jithesh","family":"Appukutty","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Addenbrooke's Hospital Cambridge University Hospitals NHS Foundation Trust Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekpemi","family":"Irune","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head &amp; Neck Surgery, Addenbrooke's Hospital Cambridge University Hospitals NHS Foundation Trust Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,10,5]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3148.2003.00443.x"},{"key":"e_1_2_11_3_1","unstructured":"NarayanS ed. PolesD MistryH Carter\u2010GrahamS AddisonJ BakerP BentleyA et al. on behalf of theSerious Hazards of Transfusion (SHOT) Steering Group.The 2018 Annual SHOT Report; 2019."},{"key":"e_1_2_11_4_1","doi-asserted-by":"crossref","unstructured":"The National Blood Transfusion Committee.National Blood Transfusion Committee Annual Report 2016\/17; 2016:1\u201016.","DOI":"10.1155\/2016\/4860284"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60631-5"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13342"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2010.202"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.12.1297"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599818757960"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"key":"e_1_2_11_11_1","volume-title":"Cambridge University Hospitals Blood Transfusion Data (2015\u201319)","author":"Transfusion Project","year":"2020"},{"key":"e_1_2_11_12_1","unstructured":"National Institute for Health and Care Excellence.Costing statement: blood transfusion implementing the NICE guideline on blood transfusion (NG24); 2015."},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2016.4056"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.10085.1"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/2110-5820-4-16"},{"key":"e_1_2_11_16_1","volume-title":"Cancer Statistics for the UK","author":"Cancer Research UK","year":"2017"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1017\/S002221511700202X"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/1916-0216-42-4"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-011-0155-5"},{"key":"e_1_2_11_20_1","doi-asserted-by":"crossref","DOI":"10.1201\/9780203731000","volume-title":"Scott\u2010Brown's Otorhinolaryngology and Head and Neck Surgery","author":"Watkinson JC","year":"2018"},{"key":"e_1_2_11_21_1","unstructured":"National Institute for Health and Care Excellence.Blood transfusion. 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