{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T02:17:18Z","timestamp":1787624238731,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T00:00:00Z","timestamp":1646784000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["134303\/2018\u20100"],"award-info":[{"award-number":["134303\/2018\u20100"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Evaluate the infectivity of Alphavirus Chikungunya and Mayaro in blood products in plaque forming units (UFP\/ml).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Arboviruses are responsible for sporadic diseases or epidemics which cause serious public health issues. Due to the high number of asymptomatic infections and high viremia, blood donors may pass on these viruses by transfusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods\/Materials<\/jats:title><jats:p>This study used blood bags that would be discarded after evaluation and certification of the absence of infections. The blood products obtained by centrifuging a unit of whole blood were called blood components. All blood bags were infected with viable viruses (previously quantified) compatible with Chikungunya and Mayaro viremia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Blood bags inoculated with both Chikungunya and Mayaro viruses were able to keep infective viruses during the processing of blood products (red blood cell concentrate, platelet concentrate and fresh frozen plasma) and also after the recommended storage for each component, which may infect individuals transfused with those.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results indicate that in order to prevent infections by Mayaro and Chikungunya viruses in blood products it is necessary to stimulate the development and use of diagnostic tests for these pathogens in donated blood.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tme.12855","type":"journal-article","created":{"date-parts":[[2022,3,10]],"date-time":"2022-03-10T06:44:08Z","timestamp":1646894648000},"page":"252-255","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Chikungunya and Mayaro infective viruses in components of blood"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8227-6227","authenticated-orcid":false,"given":"Ana Beatriz","family":"dos Anjos Souza","sequence":"first","affiliation":[{"name":"Virology Research Center, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo  Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vict\u00f3ria","family":"Thomazelli","sequence":"additional","affiliation":[{"name":"Virology Research Center, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo  Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Tadeu Moraes","family":"Figueiredo","sequence":"additional","affiliation":[{"name":"Virology Research Center, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo  Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,9]]},"reference":[{"issue":"3","key":"e_1_2_9_2_1","first-page":"4864","article-title":"Preval\u00eancia de inaptid\u00e3o sorol\u00f3gica dos doadores de sangue no hemocentro regional de Montes Claros, Minas Gerais","volume":"8","author":"Magalh\u00e3es TA d","year":"2016","journal-title":"J Res Fundam Care"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-84842004000200005"},{"key":"e_1_2_9_4_1","volume-title":"Joint Technical Note ANVISA\/SAS\/MS No. 002\/2016: Technical criteria for clinical screening of candidates for blood donation for Zika and Chikungunya virus.","author":"National Health Surveillance Agency","year":"2016"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2012.64"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-0246-2014"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2005.11.006"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2207.160116"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-03-564880"},{"key":"e_1_2_9_10_1","unstructured":"Sharp TM Roth NM Torres J et al.Chikungunya cases identified through passive surveillance and household investigations\u2014Puerto Rico May 5\u2013August 12 2014. 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