{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T02:24:57Z","timestamp":1782959097408,"version":"3.54.5"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T00:00:00Z","timestamp":1651017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005668","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Distrito Federal","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005668","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Chikungunya virus (CHIKV) is a mosquito\u2010borne alphavirus belonging to the <jats:italic>Togaviridae<\/jats:italic> family. The symptomatic infection is characterised by acute febrile disease which generally results in severe arthralgia and myalgia, however, most of the CHIKV infections remain asymptomatic. CHIKV RNA detection in asymptomatic volunteers may be responsible for the transfusion transmission of this infection, especially during outbreaks. There is no information for CHIKV seroprevalence among blood donors from the Federal District of Brazil.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>In early 2019, the Federal District of Brazil experienced a CHIKV outbreak, and this study evaluates the anti\u2010CHIKV IgM and IgG presence in a well characterised cohort of blood donors from this region.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>Blood samples were collected from 450 volunteer blood donors during a CHIKV outbreak and tested for the presence of anti\u2010CHIKV IgG and IgM antibodies using ELISA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The CHIKV seroprevalence was 0.89% (<jats:italic>n<\/jats:italic>\u00a0=\u00a04\/450) and anti\u2010CHIKV IgM prevalence was 1.11% (<jats:italic>n<\/jats:italic>\u00a0=\u00a05\/450).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The obtained results demonstrated that at least some of the blood donors have experienced CHIKV infection which can be related to a hypothetical risk of CHIKV transfusion transmission. More studies are necessary in order to examine the impact of CHIKV on blood transfusion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tme.12870","type":"journal-article","created":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T03:45:21Z","timestamp":1651117521000},"page":"338-342","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Chikungunya virus seroprevalence in asymptomatic blood donors during an outbreak in the Federal District of Brazil"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4378-6811","authenticated-orcid":false,"given":"Ana Micaelle","family":"da Silva Mendes","sequence":"first","affiliation":[{"name":"Faculty of Ceil\u00e2ndia University of Brasilia  Brasilia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1742-9359","authenticated-orcid":false,"given":"Daiani Cristina","family":"Cili\u00e3o\u2010Alves","sequence":"additional","affiliation":[{"name":"Euro\u2010American University Centre \u2013 UNIEURO  Brasilia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e1rbara Maciel Sidou","family":"Pimentel","sequence":"additional","affiliation":[{"name":"Blood Center of Brasilia  Brasilia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0805-6140","authenticated-orcid":false,"given":"Svetoslav Nanev","family":"Slavov","sequence":"additional","affiliation":[{"name":"Blood Center of Ribeir\u00e3o Preto, Faculty of Medicine of Ribeir\u00e3o Preto University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"},{"name":"Department of Internal Medicine, Faculty of Medicine of Ribeir\u00e3o Preto University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6856-4094","authenticated-orcid":false,"given":"Wildo Navegantes","family":"de Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Faculty of Ceil\u00e2ndia University of Brasilia  Brasilia Brazil"},{"name":"Center for Tropical Medicine, University of Brasilia  Brasilia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4699-164X","authenticated-orcid":false,"given":"Rodrigo","family":"Haddad","sequence":"additional","affiliation":[{"name":"Faculty of Ceil\u00e2ndia University of Brasilia  Brasilia Brazil"},{"name":"Center for Tropical Medicine, University of Brasilia  Brasilia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,27]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022\u20101317\u201081\u20102\u2010471"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(16)30385\u20101"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2019.06.002"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja14.01522"},{"key":"e_1_2_11_6_1","unstructured":"DeanAG SullivanKM SoeMM.OpenEpi: open source epidemiologic statistics for public health version.www.OpenEpi.com"},{"key":"e_1_2_11_7_1","unstructured":"BlasI de.WinEpi: Working IN EPIdemiology.http:\/\/www.winepi.net"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2018.2393"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2611.201824"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005254"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0115938"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2207.160116"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916\u2010015\u20100348\u2010x"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2021.08.042"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005319"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0009289.K"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2404.171370.M"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010020\u201005611\u20105"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12888"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2607.190846"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0243239"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.12\u20100681"}],"container-title":["Transfusion Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tme.12870","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tme.12870","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tme.12870","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T16:13:26Z","timestamp":1692634406000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tme.12870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,27]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1111\/tme.12870"],"URL":"https:\/\/doi.org\/10.1111\/tme.12870","archive":["Portico"],"relation":{},"ISSN":["0958-7578","1365-3148"],"issn-type":[{"value":"0958-7578","type":"print"},{"value":"1365-3148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,27]]},"assertion":[{"value":"2021-03-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}