{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T17:46:22Z","timestamp":1775065582764,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Australian Red Cross Lifeblood (Lifeblood) performs human erythrocyte antigen (HEA) genotyping for a subset of repeat whole\u2010blood donors through preferential selection which aims to maximise variation of results and possibility of identifying donors lacking high frequency red cell antigens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>The HEA Molecular Bead chip\u2122 assay is used by Lifeblood for donor genotyping. A review of all donor HEA genotype data from March 2019 to May 2022 (3\u2009years) was conducted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>HEA genotyping was performed for 20,185donors. Due to selective genotyping of donors, a higher frequency of R1R1 predicted phenotype was identified. However, frequencies of other red cell phenotypes were relatively similar to previous reported in the Australian population. A small number of donors with rare red cell phenotypes was identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Genotyping of blood donors provides an available pool of extended matched red blood cell products for matching to recipients. Additionally genotyping can improve the identification of donors with rare phenotypes. Whilst limitations exist, genotyping may reduce the need for labour intensive serotyping, improve blood inventory management, and may be useful in donor recruitment and retention.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tme.13044","type":"journal-article","created":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T03:59:32Z","timestamp":1714017572000},"page":"219-222","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Frequency of red blood cell phenotypes from genotyped Australian blood donors"],"prefix":"10.1111","volume":"34","author":[{"given":"Georgina","family":"Jacko","sequence":"first","affiliation":[{"name":"Pathology and Clinical Governance Australian Red Cross Lifeblood  Brisbane Queens Land Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanya","family":"Powley","sequence":"additional","affiliation":[{"name":"Pathology and Clinical Governance Australian Red Cross Lifeblood  Brisbane Queens Land Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6008-0386","authenticated-orcid":false,"given":"James","family":"Daly","sequence":"additional","affiliation":[{"name":"Pathology and Clinical Governance Australian Red Cross Lifeblood  Brisbane Queens Land Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Guidelines for transfusion and immunohaematology laboratory practice. Australian and New Zealand society of Blood Transfusion.2020."},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.21307\/immunohematology-2019-069"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13289"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2020.102968"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15599"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12476"},{"key":"e_1_2_6_8_1","volume-title":"PreciseType HEA Molecular BeadChip Test","year":"2021"},{"key":"e_1_2_6_9_1","unstructured":"Australian Red Cross Lifeblood.Blood Group Phenotypes.2021Accessed June 24 2023https:\/\/www.lifeblood.com.au\/health-professionals\/testing\/blood-groups\/phenotypes"},{"key":"e_1_2_6_10_1","volume-title":"The Blood Group Antigen FactsBook","author":"Reid ME","year":"2012"},{"key":"e_1_2_6_11_1","volume-title":"Blood Groups and Red Cell Antigens","author":"Dean L","year":"2005"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAT.0000000000000225"}],"container-title":["Transfusion Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tme.13044","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T03:56:05Z","timestamp":1719892565000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tme.13044"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,24]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1111\/tme.13044"],"URL":"https:\/\/doi.org\/10.1111\/tme.13044","archive":["Portico"],"relation":{},"ISSN":["0958-7578","1365-3148"],"issn-type":[{"value":"0958-7578","type":"print"},{"value":"1365-3148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,24]]},"assertion":[{"value":"2024-01-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}