{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:08:31Z","timestamp":1787242111753,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T00:00:00Z","timestamp":1722816000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Pregnancy in women with sickle cell disease (SCD) is associated with severe complications. Red blood cell (RBC) alloimmunisation is a worrying situation in pregnant women with SCD. This could increase the difficulty in finding a pheno\u2010compatible red blood product. Our study aimed to determine the prevalence of RBC alloantibodies in pregnant women with SCD and to determine the risk factors for alloantibodies formation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods\/Materials<\/jats:title>\n                    <jats:p>We conducted a prospective study at the \u201cCentre National de Transfusion Sanguine de Bamako\u201d from August 2022 to January 2023. For each participant, we collected important information, including obstetrical and transfusion histories. We performed ABO group, Rh and Kell phenotyping, and antibody screening in all study participants. We performed statistical analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We recruited 95 pregnant women with SCD. In our study, 62% of our participant had a history of blood transfusion. Only 23% of our pregnant women with SCD had a history of miscarriage. The prevalence of RBC alloantibodies was 14%. The main antibodies detected were anti\u2010E (38%) and pan\u2010agglutinins (23%). Miscarriage history, blood transfusion history, and pregnancy number were the main risk factors for RBC alloimmunisation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The care of pregnant women with SCD is complex and requires collaboration between haematologists, clinicians and gynaecologists. National guidelines should be implemented to make ABO and D typing, Rh and Kell phenotyping and antibody screening routine for all pregnant women. This would facilitate early detection of high\u2010risk situations. Particular attention should be paid to SCD pregnant women with miscarriage and blood transfusion histories.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/tme.13074","type":"journal-article","created":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T00:19:52Z","timestamp":1722903592000},"page":"421-427","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence of\n                    <scp>red blood cell<\/scp>\n                    alloantibodies in pregnant women with sickle cell disease in Bamako"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-0385-1550","authenticated-orcid":false,"given":"Minkoro","family":"Fomba","sequence":"first","affiliation":[{"name":"Centre National de transfusion Sanguine de Bamako  Bamako Mali"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boubacari","family":"Toure","sequence":"additional","affiliation":[{"name":"Centre de recherche et de Lutte contre la Dr\u00e9panocytose  Bamako Mali"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile Toly","family":"N'dour","sequence":"additional","affiliation":[{"name":"Centre National de r\u00e9f\u00e9rence en H\u00e9mobiologie P\u00e9rinatale  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliou","family":"Bagayoko","sequence":"additional","affiliation":[{"name":"Centre de Sant\u00e9 de r\u00e9f\u00e9rence de la commune V de Bamako  Bamako Mali"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mounirou","family":"Baby","sequence":"additional","affiliation":[{"name":"Centre de recherche et de Lutte contre la Dr\u00e9panocytose  Bamako Mali"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,5]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2008.10.002"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogrm.2019.01.006"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.41165"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpmfor.2021.08.009"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050460"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0368\u20102315(04)96624\u20100"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2013.02.014"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2013.04.067"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2022.09.046"},{"key":"e_1_2_9_11_1","volume-title":"Estimation du risque de mortalit\u00e9 Infanto\u2010juv\u00e9nile attribuable \u00e0 la dr\u00e9panocytose en Afrique subsaharienne (\u00c9tude MIDAS)","author":"Dado D","year":"2018"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.04.016"},{"key":"e_1_2_9_13_1","first-page":"133","article-title":"Katia Castetbon 2, V\u00e9ronique Goulet. 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