{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T22:07:19Z","timestamp":1790287639109,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine"],"published-print":{"date-parts":[[2026,4]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n The H antigen, precursor of the A and B blood groups, is a high\u2010prevalence antigen. Very few H antigen\u2010negative (H\u2212) blood donors are available in the United Kingdom.<\/jats:p>\n <\/jats:sec>\n \n Case Presentation<\/jats:title>\n \n We present the case of a second pregnancy in a 28\u2010year\u2010old woman with the very rare AB\n h<\/jats:sub>\n phenotype, and the presence of anti\u2010H, anti\u2010A and anti\u2010B. Only H\u2212 (O\n h<\/jats:sub>\n ) and AB\n h<\/jats:sub>\n phenotype red cells were compatible. Given the rarity of individuals with these phenotypes, there were insufficient compatible red cell units for management of a major antepartum or postpartum haemorrhage. For this high\u2010risk pregnancy, meticulous multidisciplinary team (MDT) planning took place between haematologists, obstetricians, anaesthetists, hospital laboratory staff and multiple teams within National Health Service Blood and Transplant including the National Frozen Blood Bank, Rare Donor Team and Red Cell Immunohaematology Laboratories. The MDT produced a birth management plan for various eventualities where blood transfusion may have been required. This process included the creation of our hospital's first vaginal cell salvage policy. A successful routine vaginal delivery was managed without transfusion.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n This case highlights the optimal care of a woman with an extremely rare blood group in pregnancy. The principles of management described here are also more widely applicable to women in whom transfusion is contraindicated, undeliverable or declined for other reasons.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/tme.70035","type":"journal-article","created":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T11:11:43Z","timestamp":1761217903000},"page":"199-204","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Perinatal clinical management of a rare\n \n AB\n h<\/sub>\n <\/scp>\n variant blood group"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-5134-2774","authenticated-orcid":false,"given":"Aritri","family":"Mandal","sequence":"first","affiliation":[{"name":"Department of Haematology Sheffield Teaching Hospitals NHS Foundation Trust Sheffield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Eastwood","sequence":"additional","affiliation":[{"name":"Red Cell Immunohaematology National Health Service Blood and Transplant Barnsley UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shane","family":"Grimsley","sequence":"additional","affiliation":[{"name":"International Blood Group Reference Laboratory National Health Service Blood and Transplant Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Tilley","sequence":"additional","affiliation":[{"name":"International Blood Group Reference Laboratory National Health Service Blood and Transplant Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare","family":"Samuelson","sequence":"additional","affiliation":[{"name":"Department of Haematology Sheffield Teaching Hospitals NHS Foundation Trust Sheffield UK"},{"name":"The Department of Oncology and Metabolism The University of Sheffield, Western Bank Sheffield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,23]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.TRANSCI.2023.103757"},{"key":"e_1_2_13_3_1","unstructured":"DeanL.The ABO blood group.2005Accessed June 11 2025.https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK2267\/"},{"key":"e_1_2_13_4_1","unstructured":"WinN.Guidelines for red cell transfusion in urgent situations and when serological compatibility cannot be assured. 1\u20137.2019https:\/\/nhsbtdbe.blob.core.windows.net\/umbraco\u2010assets\u2010corp\/27188\/inf437__4\u2010guidelines\u2010for\u2010red\u2010cell\u2010transfusion\u2010in\u2010urgent\u2010situations\u2010and\u2010when\u2010serological\u2010compatibility\u2010cannot\u2010be\u2010assured.pdf"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/TRF.12331"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/BLOOD.2023022894"},{"issue":"2","key":"e_1_2_13_7_1","first-page":"13","article-title":"Homozygosity for a novel FUT1 allele associated with weak H\u2010transferase activity and an H\u2010negative","volume":"32","author":"Tilley L","year":"2022","journal-title":"Transfus Med"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/TRF.14906"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/TME.13098"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542\u2010200309000\u201000021"},{"key":"e_1_2_13_11_1","first-page":"371","volume-title":"Transfusion Medicine and Hemostasis","author":"Goel R","year":"2014"},{"key":"e_1_2_13_12_1","unstructured":"The Management of Women with Red Cell Antibodies during Pregnancy (Green\u2010top Guideline No. 65) | RCOG. Accessed June 24 2025.https:\/\/www.rcog.org.uk\/guidance\/browse\u2010all\u2010guidance\/green\u2010top\u2010guidelines\/the\u2010management\u2010of\u2010women\u2010with\u2010red\u2010cell\u2010antibodies\u2010during\u2010pregnancy\u2010green\u2010top\u2010guideline\u2010no\u201065\/"}],"container-title":["Transfusion Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tme.70035","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tme.70035","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tme.70035","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T07:56:32Z","timestamp":1776153392000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tme.70035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,23]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1111\/tme.70035"],"URL":"https:\/\/doi.org\/10.1111\/tme.70035","archive":["Portico"],"relation":{},"ISSN":["0958-7578","1365-3148"],"issn-type":[{"value":"0958-7578","type":"print"},{"value":"1365-3148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,23]]},"assertion":[{"value":"2025-01-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}