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At present, West Nile virus (WNV), Usutu virus (USUV), Dengue virus (DENV) and Tick\u2010borne encephalitis virus (TBEV) are considered primary arboviral threats to blood safety in the UK and Northern Europe. Climate change and globalisation have enhanced the frequency of WNV and DENV cases being reported in Europe, furthering the likelihood of their spread to the UK. Furthermore, both TBEV and USUV have already been identified in reservoir hosts in England and the first human cases of TBEV infections acquired in England have been recently documented. Existing policy to protect the blood supply against emerging viral risks is based on donor deferral or nucleic acid test (NAT) screening for those recently returning from WNV endemic areas, only. Constant evaluation of the current policy is necessary to assess the feasibility of donor deferral if the case numbers within Europe continue to increase, and to determine if selective screening for these viruses is needed. Regardless of the testing and prevention strategies decided upon by the blood services, frequent review of these policies will be necessary to reflect the national and wider disease epidemiology of these arboviral infections.<\/jats:p>","DOI":"10.1111\/tme.70041","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T09:26:20Z","timestamp":1762334780000},"page":"10-19","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A blood safety perspective on emerging arboviral infections in the United Kingdom"],"prefix":"10.1111","volume":"36","author":[{"given":"Piya","family":"Rajendra","sequence":"first","affiliation":[{"name":"Radcliffe Department of Medicine University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannah","family":"Secret","sequence":"additional","affiliation":[{"name":"Radcliffe Department of Medicine University of Oxford  Oxford UK"},{"name":"Microbiology Services NHS Blood and Transplant  Colindale UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su","family":"Brailsford","sequence":"additional","affiliation":[{"name":"Microbiology Services NHS Blood and Transplant  Colindale UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya","family":"Golubchik","sequence":"additional","affiliation":[{"name":"Big Data Institute, Nuffield Department of Medicine University of Oxford  Oxford UK"},{"name":"Sydney Infectious Diseases Institute (Sydney ID), School of Medical Sciences, Faculty of Medicine and Health University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Simmonds","sequence":"additional","affiliation":[{"name":"Nuffield Department of Medicine University of Oxford  Oxford UK"},{"name":"Institute of Biomedicine, Faculty of Medicine University of Turku and Turku University Hospital  Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heli","family":"Harvala","sequence":"additional","affiliation":[{"name":"Radcliffe Department of Medicine University of Oxford  Oxford UK"},{"name":"Microbiology Services NHS Blood and Transplant  Colindale UK"},{"name":"Institute of Biomedicine, Faculty of Medicine University of Turku and Turku University Hospital  Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,5]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-019-0222-5"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanepe.2021.100230"},{"key":"e_1_2_15_4_1","volume-title":"Fields virology: Emerging viruses","author":"Howley PM","year":"2020"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-13258-2"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12216859"},{"key":"e_1_2_15_7_1","unstructured":"SmithburnK HughesT BurkeA PaulJ.A neurotropic virus isolated from the blood of a native of Uganda.1940."},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1956.5.579"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2001.tb02692.x"},{"key":"e_1_2_15_10_1","doi-asserted-by":"crossref","unstructured":"MarbergK GoldbltjmN SterkVV Jasinska\u2010klingbehgW KlingbergMA.The natural history of West Nile fever. 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