{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:38:45Z","timestamp":1786714725016,"version":"build-2736575974"},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["20KC1002"],"award-info":[{"award-number":["20KC1002"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Packed red blood cells (PRBC) are stored at 2\u00b0C\u20136\u00b0C to ensure quality. Improper temperature control during PRBC transport reduces the quality of downstream blood products and wastes PRBC units. This study evaluated the suitability of the BioBox LAB10 for in\u2010hospital PRBC transport.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Temperatures of the box interior and simulated formulation were measured to assess cooling capabilities. Quality was evaluated by measuring red blood cell count, haemoglobin concentration, haematocrit, pH, potassium concentration, and ATP concentration of PRBC samples. The storage capacity, size, weight, and cost of the BioBox was compared with that of the ATR700.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The BioBox cooled to \u22646\u00b0C within 14 min. PRBC temperature remained \u22646\u00b0C for approximately 19 h. None of the quality parameters, including ATP concentration, differed significantly between samples stored in the BioBox or in a refrigerator. The BioBox is smaller, lighter, and 84% less expensive than the ATR700, with an equivalent storage capacity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The BioBox effectively maintains temperature and PRBC quality during transport and provides a practical solution for in\u2010hospital transport of blood for transfusion owing to its compact, lightweight design, and affordability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/tme.70073","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:09:01Z","timestamp":1772996941000},"page":"406-410","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of the\n                    <scp>BioBox LAB10<\/scp>\n                    for maintaining temperature and quality of packed red blood cells during in\u2010hospital storage and transport"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6748-4546","authenticated-orcid":false,"given":"Yohei","family":"Sakai","sequence":"first","affiliation":[{"name":"Graduate School of Health Sciences Fujita Health University  Toyoake Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takato","family":"Ozeki","sequence":"additional","affiliation":[{"name":"Department of Blood Transfusion Fujita Health University Hospital  Toyoake Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6307-3379","authenticated-orcid":false,"given":"Hideaki","family":"Matsuura","sequence":"additional","affiliation":[{"name":"Graduate School of Health Sciences Fujita Health University  Toyoake Japan"},{"name":"Department of Blood Transfusion Fujita Health University Hospital  Toyoake Japan"},{"name":"Department of Cellular and Molecular Biology Fujita Health University School of Medical Sciences  Toyoake Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rie","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Department of Blood Transfusion Fujita Health University Hospital  Toyoake Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuya","family":"Ishihara","sequence":"additional","affiliation":[{"name":"Department of Blood Transfusion Fujita Health University Hospital  Toyoake Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Doi","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology Fujita Health University School of Medical Sciences  Toyoake Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Miura","sequence":"additional","affiliation":[{"name":"Department of Blood Transfusion Fujita Health University Hospital  Toyoake Japan"},{"name":"Department of Transfusion Medicine and Cell Therapy Fujita Health University School of Medicine  Toyoake Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"Biological Agents Standard. Notification No. 380","author":"Ministry of Health, Labour and Welfare, Japan","year":"2024"},{"key":"e_1_2_11_3_1","volume-title":"Guideline for the Implementation of Blood Transfusion Therapy","author":"Blood and Blood Products Division, Pharmaceutical Safety and Environmental Health Bureau, Ministry of Health, Labour and Welfare, Japan","year":"2020"},{"issue":"1","key":"e_1_2_11_4_1","first-page":"33","article-title":"Development of new transportation equipment for supplying red blood cells to a remote Island (Ogasawara Islands). Article in Japanese","volume":"38","author":"Ametani R","year":"2015","journal-title":"Ketsuekijigyou"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14444"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3925\/jjtc.69.448"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537\u20102995.2012.03890.x"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423\u20100410.2012.01589.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917\u2010017\u20101058\u20108"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0887\u20107963(92)70166\u20107"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000357986"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.4236\/ojbd.2020.102004"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537\u20102995.2012.03807.x"}],"container-title":["Transfusion Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tme.70073","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tme.70073","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tme.70073","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:14:25Z","timestamp":1786713265000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tme.70073"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,6]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1111\/tme.70073"],"URL":"https:\/\/doi.org\/10.1111\/tme.70073","archive":["Portico"],"relation":{},"ISSN":["0958-7578","1365-3148"],"issn-type":[{"value":"0958-7578","type":"print"},{"value":"1365-3148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,6]]},"assertion":[{"value":"2025-10-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}