{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T11:55:29Z","timestamp":1792065329172,"version":"4.4.0"},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Since the COVID\u201019 pandemic, demand for blood products has remained high, while donations have declined. Institutional policies guiding the use of these products may affect their availability, utilisation and waste. We surveyed blood banks (BBs) in the United States (U.S.) to assess policies and practices related to cryoprecipitate compatibility and to characterise experiences with administration, shortages and waste.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An 11\u2010question online survey was distributed to U.S. BBs via Qualtrics. Responses were exported to Excel and analysed using descriptive statistics. Variables are reported as frequencies and percentages.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 241 BBs, 82 responded (34%). Thirty\u2010seven (45%) served community hospitals, 31 (38%) served academic hospitals and 55 (69%) served both adult and paediatric populations. Thirty (38%) BBs reported preferentially administering ABO type\u2010specific cryoprecipitate when available, although none reported restricting transfusion exclusively to type\u2010specific units under all circumstances. Eighteen (23%) limited the number of out\u2010of\u2010group units per patient within 24\u2009h. Ten (13%) BBs reported shortages occurring at least 3\u20135 times per year. During shortages, 25 (61%) BBs proactively screened orders, and 14 (34%) used fibrinogen concentrate as an alternative. Annual wastage varied, with 12 (15%) BBs discarding more than 50 pooled units, often because unused units were thawed for massive transfusion protocols (MTPs). Strategies to reduce wastage included thawing units later in the MTP cycle, proactive order screening and supplementation with fibrinogen concentrate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although a subset of BBs reported substantial shortages of cryoprecipitate, some institutions reported significant waste. Targeted strategies, such as limiting units administered, proactively reviewing orders, offering alternative products and modifying thawing policies for MTPs, may improve efficiency and reduce waste.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/tme.70079","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T06:00:34Z","timestamp":1775628034000},"page":"503-510","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cryoprecipitate utilisation, shortages and institutional policies in the United States: A survey of practices and policies"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9906-9694","authenticated-orcid":false,"given":"Chinelo P.","family":"Onyenekwu","sequence":"first","affiliation":[{"name":"Department of Pathology Medical College of Wisconsin  Milwaukee Wisconsin USA"},{"name":"University of Wisconsin\u2010Madison Department of Pathology and Laboratory Medicine  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariam","family":"Ratiani","sequence":"additional","affiliation":[{"name":"Department of Pathology Medical College of Wisconsin  Milwaukee Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenna","family":"Wade","sequence":"additional","affiliation":[{"name":"Department of Pathology Medical College of Wisconsin  Milwaukee Wisconsin USA"},{"name":"Versiti  Milwaukee Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6768-736X","authenticated-orcid":false,"given":"Angela","family":"Treml","sequence":"additional","affiliation":[{"name":"Department of Pathology Medical College of Wisconsin  Milwaukee Wisconsin USA"},{"name":"Versiti  Milwaukee Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16125"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14415"},{"key":"e_1_2_10_4_1","volume-title":"Standards for Blood Banks and Transfusion Services","author":"AABB","year":"2024"},{"key":"e_1_2_10_5_1","volume-title":"Circular of Information for the Use of Human Blood and Blood Components","author":"AABB, American Red Cross, America's Blood Centers, Armed Services Blood Program","year":"2024"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17116"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13256"},{"key":"e_1_2_10_8_1","volume-title":"Trends Impacting the Nation's Blood Supply [Internet]. Washington, DC: America's Blood Centers","author":"America's Blood Centers","year":"2023"},{"key":"e_1_2_10_9_1","volume-title":"Adequacy of the National Blood Supply: Report to Congress 2020","author":"U.S. Department of Health and Human Services","year":"2020"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000005393"},{"key":"e_1_2_10_11_1","volume-title":"Red Cross, America's Blood Centers, AABB Say U.S. Faces Critical Blood and Platelet Shortages","author":"American Hospital Association","year":"2024"},{"key":"e_1_2_10_12_1","unstructured":"American Red Cross.Help Prevent Blood Shortages in 2025 by Giving Blood or Platelets Now[Monograph on the Internet].2025.https:\/\/www.redcross.org\/local\/california\/los\u2010angeles\/about\u2010us\/news\u2010and\u2010events\/press\u2010releases\/red\u2010cross\u2010\u2010help\u2010prevent\u2010blood\u2010shortages\u2010in\u20102025\u2010by\u2010giving\u2010blood\u2010.html?srsltid=AfmBOoooX6Yx0xmFc1\u2010vMKQFW7AsvFAcXluL1YGXANcoPuBDUPd5G5zP"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17861"},{"key":"e_1_2_10_14_1","unstructured":"America's Blood Centers.Current National Blood Supply[Monograph on the Internet].2025.https:\/\/americasblood.org\/for-donors\/americas-blood-supply\/"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.18434"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2008.01826.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqaa042"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10916-021-01719-6"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqae073"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.617500"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1660852"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH15-12-0964"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-1756704"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2021.06.006"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12045"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-10-833988"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.21037\/aob-21-83"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2010.175"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17319"},{"key":"e_1_2_10_30_1","first-page":"393","article-title":"When is ABO\u2010incompatible plasma safe to transfuse? 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