{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T02:06:37Z","timestamp":1785549997795,"version":"3.56.0"},"reference-count":26,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Viral hepatitis remains a serious risk to transfusion safety, despite being considerably reduced by donor screening. Objectives: The aim of this study was to evaluate the seroprevalence of HBV and HCV among asymptomatic blood donors in Saudi Arabia in the past 15\u2009years (2010\u20132025). A literature search has been conducted on seven databases. Prevalence rates with 95% confidence intervals (CIs) were pooled via a random effects model. Twelve studies, examining 597\u2009820 blood donors, were included in this study. The overall pooled prevalence rate of HBV and HCV among blood donors was 0.455% (95% CI: 0.334%\u20130.619%) and 0.195% (95% CI: 0.130%\u20130.292%), respectively. Although a high heterogeneity was detected across studies (\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    &gt;80%,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.000), sensitivity analysis revealed strong reliability, and no publication bias was detected. Subgroups and meta\u2010regression analyses demonstrated that publication period, geographic location, and diagnostic methods were the main factors contributing to heterogeneity in prevalence estimates for HBV and HCV. According to our findings, the prevalence of positive blood donors for HBV and HCV is low across Saudi Arabia. We suggest that vaccination campaigns and public education regarding the modes of transmission should be improved in order to reduce the prevalence of blood\u2010borne viruses.\n                  <\/jats:p>","DOI":"10.1111\/tme.70107","type":"journal-article","created":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T01:26:21Z","timestamp":1785547581000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Seroprevalence of hepatitis B and C in asymptomatic blood donors in Saudi Arabia: A systematic review and meta\u2010analysis"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9028-9415","authenticated-orcid":false,"given":"Mohammad S.","family":"Alzahrani","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacy College of Pharmacy, Taif University  Taif Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4192-1653","authenticated-orcid":false,"given":"Majed A.","family":"Algarni","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy College of Pharmacy, Taif University  Taif Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1199-0519","authenticated-orcid":false,"given":"Safa","family":"Boujemaa","sequence":"additional","affiliation":[{"name":"Department of Research Publishing Biologica Training and Consulting  La Marsa Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,31]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15020533"},{"key":"e_1_2_12_3_1","unstructured":"World Health Organization.Global hepatitis report 2024: action for access in low\u2010 and middle\u2010income countries. Published online2024."},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.15698\/mic2016.09.527"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(23)01320\u2010X"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinre.2020.101596"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560\u20107917.ES.2020.25.29.1900537"},{"key":"e_1_2_12_8_1","unstructured":"World Health Organization.Global Database on Blood Safety: Summary Report 2011.https:\/\/www.who.int\/publications\/m\/item\/gdbs-summary-report-2011"},{"issue":"2","key":"e_1_2_12_9_1","first-page":"41","article-title":"Prevalence of hepatitis B and C in donated blood from the Jazan region of Saudi Arabia","volume":"20","author":"Abdullah SM","year":"2013","journal-title":"Malays J Med Sci"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.4172\/2155\u20109864.1000280"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.15537\/smj.2022.43.12.20220634"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.46658\/JBIMES\u201020\u201006"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7109.629"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423\u20100410.2010.01426.x"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010021\u201006505\u2010w"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.25259\/ijmr_285_24"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0307101"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijpvm.ijpvm_260_18"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.puhe.2021.07.011"},{"issue":"8","key":"e_1_2_12_21_1","first-page":"674","article-title":"Prevalence and trend of hepatitis C virus infection among blood donors in Iran: a systematic review and meta\u2010analysis","volume":"18","author":"Khodabandehloo M","year":"2013","journal-title":"J Res Med Sci"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2008.01.010"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.4103\/sjhs.sjhs_197_19"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.51758\/AGJSR\u201004\u20102020\u20100016"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.4236\/health.2015.74054"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.3343\/alm.2019.39.1.81"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2019.19325"}],"container-title":["Transfusion Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tme.70107","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tme.70107","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tme.70107","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T01:26:23Z","timestamp":1785547583000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tme.70107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,31]]},"references-count":26,"alternative-id":["10.1111\/tme.70107"],"URL":"https:\/\/doi.org\/10.1111\/tme.70107","archive":["Portico"],"relation":{},"ISSN":["0958-7578","1365-3148"],"issn-type":[{"value":"0958-7578","type":"print"},{"value":"1365-3148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,31]]},"assertion":[{"value":"2026-03-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"tme.70107"}}