{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T19:26:44Z","timestamp":1699471604355},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,10,29]],"date-time":"2012-10-29T00:00:00Z","timestamp":1351468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To explore the financial implications of applying the <jats:styled-content style=\"fixed-case\">WHO<\/jats:styled-content> guidelines for the nutritional management of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected children in a rural <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>outh <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>frican <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> programme.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">WHO<\/jats:styled-content> guidelines describe <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>utritional <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>are <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>lans (<jats:styled-content style=\"fixed-case\">NCP<\/jats:styled-content>s) for three categories of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected children: <jats:styled-content style=\"fixed-case\">NCP<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>: growing adequately; <jats:styled-content style=\"fixed-case\">NCP<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>: weight\u2010for\u2010age z\u2010score (<jats:styled-content style=\"fixed-case\">WAZ<\/jats:styled-content>) \u2264\u22122 but no evidence of severe acute malnutrition (<jats:styled-content style=\"fixed-case\">SAM<\/jats:styled-content>), confirmed weight loss\/growth curve flattening, or condition with increased nutritional needs (e.g. tuberculosis); <jats:styled-content style=\"fixed-case\">NCP<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>:<jats:styled-content style=\"fixed-case\"> SAM<\/jats:styled-content>. In resource\u2010constrained settings, children requiring <jats:styled-content style=\"fixed-case\">NCP<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">B<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">NCP<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content> usually need supplementation to achieve the additional energy recommendation. We estimated the proportion of children initiating antiretroviral treatment (<jats:styled-content style=\"fixed-case\">ART<\/jats:styled-content>) in the <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>labisa <jats:styled-content style=\"fixed-case\">HIV P<\/jats:styled-content>rogramme who would have been eligible for supplementation in 2010. The cost of supplying 26\u2010weeks supplementation as a proportion of the cost of supplying <jats:styled-content style=\"fixed-case\">ART<\/jats:styled-content> to the same group was calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 251 children aged 6\u00a0months to 14\u00a0years initiated <jats:styled-content style=\"fixed-case\">ART<\/jats:styled-content>. Eighty\u2010eight required 6\u2010month <jats:styled-content style=\"fixed-case\">NCP<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>, including 41 with a <jats:styled-content style=\"fixed-case\">WAZ<\/jats:styled-content> \u2264\u22122 (no evidence of <jats:styled-content style=\"fixed-case\">SAM<\/jats:styled-content>) and 47 with a <jats:styled-content style=\"fixed-case\">WAZ<\/jats:styled-content> &gt;\u22122 with co\u2010existent morbidities including tuberculosis. Additionally, 25 children had <jats:styled-content style=\"fixed-case\">SAM<\/jats:styled-content> and required 10\u2010weeks <jats:styled-content style=\"fixed-case\">NCP<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content> followed by 16\u2010weeks <jats:styled-content style=\"fixed-case\">NCP<\/jats:styled-content>\u2010B. Thus, 113 of 251 (45%) children were eligible for nutritional supplementation at an estimated overall cost of $11\u00a0136, using 2010 exchange rates. These costs are an estimated additional 11.6% to that of supplying 26\u2010week <jats:styled-content style=\"fixed-case\">ART<\/jats:styled-content> to the 251 children initiated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>It is essential to address nutritional needs of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected children to optimise their health outcomes. Nutritional supplementation should be integral to, and budgeted for, in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> programmes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.12006","type":"journal-article","created":{"date-parts":[[2012,10,30]],"date-time":"2012-10-30T01:27:25Z","timestamp":1351560445000},"page":"45-52","source":"Crossref","is-referenced-by-count":7,"title":["Nutritional supplementation: the additional costs of managing children infected with HIV in resource\u2010constrained settings"],"prefix":"10.1111","volume":"18","author":[{"given":"G.","family":"Cobb","sequence":"first","affiliation":[{"name":"Africa Centre for Health and Populations Studies University of KwaZulu\u2010Natal KwaZulu\u2010Natal South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. 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