{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T00:02:27Z","timestamp":1778371347285,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,12,20]],"date-time":"2012-12-20T00:00:00Z","timestamp":1355961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the seroprevalence of varicella\u2010zoster viral (<jats:styled-content style=\"fixed-case\">VZV<\/jats:styled-content>) infections in schoolchildren from the Cochabamba region (Bolivia), and its association with socio\u2010demographic variables, socio\u2010economic status and geographical location.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seroepidemiological survey (<jats:italic>n<\/jats:italic>\u00a0=\u00a0436) on <jats:styled-content style=\"fixed-case\">VZV<\/jats:styled-content> of schoolchildren living in the Cochabamba region of Bolivia in 2010. An <jats:styled-content style=\"fixed-case\">ELISA<\/jats:styled-content> test was used to measure varicella antibodies. Parents or guardians completed a questionnaire regarding socio\u2010demographic information (age, gender, living area, parental educational level, presence of siblings and number of family members in the household), and a blood sample was collected from each child to check for <jats:styled-content style=\"fixed-case\">VZV<\/jats:styled-content> antibodies. A descriptive and bivariate analysis was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The global prevalence of <jats:styled-content style=\"fixed-case\">VZV<\/jats:styled-content> was 78.2% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 74.3\u201382.1). It was higher in females (82.1%), pre\u2010adolescents (aged 10.1\u201313\u00a0years: 81.4%) and adolescents (aged &gt;13\u00a0years: 80.2%), in children with less well\u2010educated parents (81.3% to 81.6%), in warmer municipalities (81.4% to 82.2%), in rural areas (80.0%), in children with siblings (80.1%), those who although the latter association was not statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The prevalence of <jats:styled-content style=\"fixed-case\">VZV<\/jats:styled-content> infection in childhood was relatively high for a tropical country, and much closer to that of temperate countries prior to the introduction of varicella vaccine into vaccination programmes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.12040","type":"journal-article","created":{"date-parts":[[2012,12,21]],"date-time":"2012-12-21T19:50:22Z","timestamp":1356119422000},"page":"296-302","source":"Crossref","is-referenced-by-count":10,"title":["Seroprevalence of varicella\u2010zoster virus infection in children from Cochabamba: tropical or temperate pattern?"],"prefix":"10.1111","volume":"18","author":[{"given":"Cristina","family":"Masuet\u2010Aumatell","sequence":"first","affiliation":[{"name":"International Health Center and Travel Medicine Clinic University Hospital of Bellvitge Bellvitge Spain"},{"name":"Department of Clinical Sciences University of Barcelona Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep M\u00aa","family":"Ramon\u2010Torrell","sequence":"additional","affiliation":[{"name":"International Health Center and Travel Medicine Clinic University Hospital of Bellvitge Bellvitge Spain"},{"name":"Department of 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