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Adaptation of existing preventive guidelines to local environments will become a priority for <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> treatment programmes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Guidance from the <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>orld <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ealth <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>rganization, a focused evidenced\u2010based literature review, <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>otswana national guidelines, <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>otswana\u2010specific morbidity and mortality data and centre\u2010specific data were used to adapt a published general primary care package for limited\u2010resource areas to our centre's specific setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The preventive care package contains recommendations on tuberculosis prevention, malnutrition, depression, cervical and breast cancer, hepatitis <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content> coinfection, cardiovascular risk factors, external injury prevention, domestic violence screening, tobacco and substance\u2010abuse counselling, contraception and screening and treatment of sexually transmitted infections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This preventive care package addresses the comprehensive health needs of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected adults in the <jats:styled-content style=\"fixed-case\">FMC<\/jats:styled-content> in an evidence\u2010based manner. 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