{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T04:19:25Z","timestamp":1697343565930},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,3,7]],"date-time":"2013-03-07T00:00:00Z","timestamp":1362614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate a new tool for the monitoring of Visceral Leishmaniasis (<jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content>) treatment outcomes in primary healthcare (PHC) settings, adapted from the standardised <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>etrospective <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>uarterly <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ohort <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>onitoring done in tuberculosis control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We developed standard case definitions for early and late <jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content> treatment outcomes, a single register allowing for one\u2010line entry per patient as registration tool, and quarterly reporting formats for the clinical outcomes. We pilot\u2010tested these tools in three <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndian <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>rimary <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ealth <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>entres and two <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>epalese district hospitals, as well as in a charity <jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content> treatment centre and a university hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data collection for early treatment outcome was easily implemented but information on late treatment outcome was hard to obtain. Effectiveness of Miltefosine under routine care conditions was about 87% at end of treatment, and 76% at 6\u00a0months post\u2010treatment related to the high number of patients lost to follow up at the latter end point.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A retrospective cohort monitoring methodology is conceptually a good framework for monitoring clinical outcomes for chronic conditions as <jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content>. The monitoring of early outcomes of <jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content> treatment is perfectly feasible in <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>rimary <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>are settings. The completeness of information on late outcomes can be improved by a number of strategies that remain to be field tested. Generally, clinical outcome monitoring should be strengthened in the <jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content> control programmes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.12092","type":"journal-article","created":{"date-parts":[[2013,3,7]],"date-time":"2013-03-07T06:52:47Z","timestamp":1362639167000},"page":"725-733","source":"Crossref","is-referenced-by-count":7,"title":["Retrospective <scp>Q<\/scp>uarterly <scp>C<\/scp>ohort <scp>M<\/scp>onitoring for patients with <scp>V<\/scp>isceral <scp>L<\/scp>eishmaniasis in the <scp>I<\/scp>ndian subcontinent: outcomes of a pilot project"],"prefix":"10.1111","volume":"18","author":[{"given":"Bart","family":"Ostyn","sequence":"first","affiliation":[{"name":"Institute of Tropical Medicine Antwerp Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paritosh","family":"Malaviya","sequence":"additional","affiliation":[{"name":"Institute of Medical Sciences Banaras Hindu University Varanasi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Epco","family":"Hasker","sequence":"additional","affiliation":[{"name":"Institute of Tropical Medicine Antwerp Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surendra","family":"Uranw","sequence":"additional","affiliation":[{"name":"B. 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