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On both occasions, the presence of mono\u2010 or multiple infections and intensities of infection were compared with nutritional parameters and with serum cytokines or chemokines as markers for inflammatory, regulatory or Th1\u2010 or Th2\u2010type immune responses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Before treatment, we were not able to associate any altered nutritional parameters with increased inflammatory responses, and highest intensities of infection were found in eutrophic participants with multiple infections. In contrast, major changes in serum Th2\u2010type chemokine levels were measured in individuals infected with intestinal helminths and\/or <jats:italic>S.\u00a0mansoni,<\/jats:italic> and resulted in significantly higher <jats:styled-content style=\"fixed-case\">CCL<\/jats:styled-content>11 and <jats:styled-content style=\"fixed-case\">CCL<\/jats:styled-content>17 concentrations, both before treatment and after reinfection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The driving force for these elevated type 2 serum chemokine concentrations was an <jats:italic>S.\u00a0mansoni<\/jats:italic> infection and faecal egg counts significantly correlated with serum <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201010 concentrations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.12095","type":"journal-article","created":{"date-parts":[[2013,3,15]],"date-time":"2013-03-15T21:03:06Z","timestamp":1363381386000},"page":"750-760","source":"Crossref","is-referenced-by-count":21,"title":["Serum <scp>CCL<\/scp>11 (eotaxin\u20101) and <scp>CCL<\/scp>17 (<scp>TARC<\/scp>) are serological indicators of multiple helminth infections and are driven by <i>Schistosoma mansoni<\/i> infection in humans"],"prefix":"10.1111","volume":"18","author":[{"given":"Stefan M.","family":"Geiger","sequence":"first","affiliation":[{"name":"Universidade Federal de Minas Gerais, Instituto de Ci\u00eancias Biol\u00f3gicas Belo Horizonte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Jardim\u2010Botelho","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz, Centro de Pesquisas Ren\u00e9 Rachou Belo Horizonte Brazil"},{"name":"Universidade Federal de Sergipe, Hospital 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