{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:58:51Z","timestamp":1791356331933,"version":"4.3.1"},"reference-count":35,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,5,18]],"date-time":"2013-05-18T00:00:00Z","timestamp":1368835200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A meningococcal serogroup <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content> polysaccharide\/tetanus toxoid conjugate vaccine (<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>s<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TT<\/jats:styled-content>) (<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>en<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>fri<jats:styled-content style=\"fixed-case\">V<\/jats:styled-content>ac<jats:sup>\u2122<\/jats:sup>) is being deployed in countries of the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>frican meningitis belt. Experience with other polysaccharide\/protein conjugate vaccines has shown that an important part of their success has been their ability to prevent the acquisition of pharyngeal carriage and hence to stop transmission and induce herd immunity. If <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>s<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TT<\/jats:styled-content> is to achieve the goal of preventing epidemics, it must be able to prevent the acquisition of pharyngeal carriage as well as invasive meningococcal disease and whether <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>s<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TT<\/jats:styled-content> can prevent pharyngeal carriage needs to be determined. To address this issue, a consortium (the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>frican <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>eningococcal <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>arriage (<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>en<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>fri<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ar) consortium) was established in 2009 to investigate the pattern of meningococcal carriage in countries of the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>frican meningitis belt prior to and after the introduction of <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>s<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TT<\/jats:styled-content>. This article describes how the consortium was established, its objectives and the standardised field and laboratory methods that were used to achieve these objectives. The experience of the <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>en<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>fri<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ar consortium will help in planning future studies on the epidemiology of meningococcal carriage in countries of the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>frican meningitis belt and elsewhere.<\/jats:p>","DOI":"10.1111\/tmi.12125","type":"journal-article","created":{"date-parts":[[2013,5,18]],"date-time":"2013-05-18T07:11:05Z","timestamp":1368861065000},"page":"968-978","source":"Crossref","is-referenced-by-count":32,"title":["Meningococcal carriage in the <scp>A<\/scp>frican meningitis belt"],"prefix":"10.1111","volume":"18","author":[{"name":"The MenAfriCar consortium","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,5,18]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"BastaN(2011)The epidemiology of Neisseria meningitidis carriage in Bamako Mali prior to the introduction of a newly developed meningococcal serogroup A vaccine. 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