{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T02:49:30Z","timestamp":1782874170057,"version":"3.54.5"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T00:00:00Z","timestamp":1373414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Elias Pavlopoulos"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2013,9]]},"abstract":"Abstract<\/jats:title>Objectives<\/jats:title>To understand patients' challenges in adhering to treatment for MDR<\/jats:styled-content>\u2010TB<\/jats:styled-content>\/HIV<\/jats:styled-content> co\u2010infection within the context of their life circumstances and access to care and support.<\/jats:p><\/jats:sec>Methods<\/jats:title>Qualitative study using in\u2010depth interviews with 12 HIV<\/jats:styled-content>\/MDR<\/jats:styled-content>\u2010TB<\/jats:styled-content> co\u2010infected patients followed in a M<\/jats:styled-content>\u00e9decins S<\/jats:styled-content>ans F<\/jats:styled-content>ronti\u00e8res (MSF<\/jats:styled-content>) clinic in Mumbai, India, five lay caregivers and ten health professionals. The data were thematically analysed along three dimensions of patients' experience of being and staying on treatment: physiological, psycho\u2010social and structural.<\/jats:p><\/jats:sec>Results<\/jats:title>By the time patients and their families initiate treatment for co\u2010infection, their financial and emotional resources were often depleted. Side effects of the drugs were reported to be severe and debilitating, and patients expressed the burden of care and stigma on the social and financial viability of the household. Family caregivers were crucial to maintaining the mental and physical health of patients, but reported high levels of fatigue and stress. M<\/jats:styled-content>\u00e9decins S<\/jats:styled-content>ans F<\/jats:styled-content>ronti\u00e8res providers recognised that the barriers to patient adherence were fundamentally social, rather than medical, yet were limited in their ability to support patients and their families.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The treatment of MDR<\/jats:styled-content>\u2010TB<\/jats:styled-content> among HIV<\/jats:styled-content>\u2010infected patients on antiretroviral therapy is hugely demanding for patients, caregivers and families. Current treatment regimens and case\u2010holding strategies are resource intensive and require high levels of support from family and lay caregivers to encourage patient adherence and retention in care.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.12146","type":"journal-article","created":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T06:53:32Z","timestamp":1373439212000},"page":"1128-1133","source":"Crossref","is-referenced-by-count":66,"title":["\u2018I cry every day\u2019: experiences of patients co\u2010infected with HIV<\/scp> and multidrug\u2010resistant tuberculosis"],"prefix":"10.1111","volume":"18","author":[{"given":"Petros","family":"Isaakidis","sequence":"first","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheela","family":"Rangan","sequence":"additional","affiliation":[{"name":"The Maharashtra Association of Anthropological Sciences Pune India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anagha","family":"Pradhan","sequence":"additional","affiliation":[{"name":"Independent Researcher Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Ladomirska","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"Reid","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res Operational Research Unit Luxembourg Luxembourg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina","family":"Kielmann","sequence":"additional","affiliation":[{"name":"Institute of International Health & Development Queen Margaret University Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tube.2012.02.009"},{"key":"e_1_2_7_3_1","first-page":"222","article-title":"Treatment outcome of TB\/HIV positive and TB\/HIV negative patients on directly observed treatment, short course (DOTS) in Sagamu","volume":"15","author":"Daniel OJ","year":"2006","journal-title":"Nigerian journal of medicine"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2648.2011.05934.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-10-651"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0B013E31822D490A"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10865-007-9147-y"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0028066"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0040781"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0006914"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2005.19.526"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0030438"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0040238"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200007070-00015"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(09)70041-6"},{"key":"e_1_2_7_16_1","unstructured":"RNTCP Annual Status Report(2012)TB Control India."},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-8-11"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0040037"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.12.0537"},{"key":"e_1_2_7_20_1","unstructured":"World Health Organization (WHO)(2010)Antiretroviral Therapy for HIV Infection in Adults and Adolescents. 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