{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:19:38Z","timestamp":1787015978628,"version":"build-2736575974"},"reference-count":44,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,9,23]],"date-time":"2013-09-23T00:00:00Z","timestamp":1379894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To quantify the incidence of and risk factors for neonatal jaundice among infants referred for care from a rural, low\u2010resource, population\u2010based cohort in southern\n                      <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>\n                      epal.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Study participants were 18\u00a0985 newborn infants born in\n                      <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                      arlahi\n                      <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>\n                      istrict in southern\n                      <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>\n                      epal from May 2003 through January 2006 who participated in a cluster\u2010randomised, placebo\u2010controlled, community\u2010based trial to evaluate the effect of newborn chlorhexidine cleansing on neonatal mortality and morbidity. Jaundice was assessed based on visual assessment of the infant by a study worker and referral for care. Adjusted relative risks (\n                      <jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content>\n                      ) were estimated to identify risk factors for referral for neonatal jaundice using Poisson regression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The incidence of referral for neonatal jaundice was 29.3 per 1000 live births (95% confidence interval: 26.9, 31.7). Male sex, high birth weight, breastfeeding patterns, warm air temperature, primiparity, skilled birth attendance, place of delivery, prolonged labour, oil massage, paternal education and ethnicity were significant risk factors (\n                      <jats:italic>P<\/jats:italic>\n                      \u2010values\u00a0&lt;\u00a00.01). After multivariable adjustment, sex, birth weight, difficulty feeding, prolonged labour, primiparity, oil massage, ambient air temperature and ethnicity remained important factors. Among infants with difficulty feeding, exclusive breastfeeding was a risk factor for neonatal jaundice, whereas exclusive breastfeeding was protective among infants with no report of difficulty feeding.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Several known risk factors for neonatal jaundice in a low\u2010resource setting were confirmed in this study. Unique observed associations of jaundice with ambient air temperature and oil massage may be explained by the opportunity for phototherapy based on the cultural practices of this study population. Future research should investigate the role of an infant's difficulty in feeding as a potential modifier in the association between exclusive breastfeeding and jaundice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/tmi.12189","type":"journal-article","created":{"date-parts":[[2013,10,11]],"date-time":"2013-10-11T18:09:52Z","timestamp":1381514992000},"page":"1317-1328","source":"Crossref","is-referenced-by-count":70,"title":["Incidence of and risk factors for neonatal jaundice among newborns in southern\n                    <scp>N<\/scp>\n                    epal"],"prefix":"10.1111","volume":"18","author":[{"given":"Carolyn G.","family":"Scrafford","sequence":"first","affiliation":[{"name":"Department of International Health, Global Disease Epidemiology and Control Johns Hopkins Bloomberg School of Public Health Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke C.","family":"Mullany","sequence":"additional","affiliation":[{"name":"Department of International Health, Global Disease Epidemiology and Control Johns Hopkins Bloomberg School of Public Health Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Katz","sequence":"additional","affiliation":[{"name":"Department of International Health, Global Disease Epidemiology and Control Johns Hopkins Bloomberg School of Public Health Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subarna K.","family":"Khatry","sequence":"additional","affiliation":[{"name":"Department of International Health, Global Disease Epidemiology and Control Johns Hopkins Bloomberg School of Public Health Baltimore MD USA"},{"name":"Nepal Nutrition Intervention Project \u2013 Sarlahi Kathmandu Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven C.","family":"LeClerq","sequence":"additional","affiliation":[{"name":"Department of International Health, Global Disease Epidemiology and Control Johns Hopkins Bloomberg School of Public Health Baltimore MD USA"},{"name":"Nepal Nutrition Intervention Project \u2013 Sarlahi Kathmandu Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary L.","family":"Darmstadt","sequence":"additional","affiliation":[{"name":"Global Development Division Family Health Program Bill and Melinda Gates Foundation Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James M.","family":"Tielsch","sequence":"additional","affiliation":[{"name":"Department of Global Health School of Public Health and Health Services George Washington University Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,9,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.114.1.297"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.3.763"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.114.1.297"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1891\/0730-0832.26.5.327"},{"key":"e_1_2_6_6_1","first-page":"601","article-title":"Glucose\u20106\u2010phosphate dehydrogenase deficiency. 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