{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T18:04:44Z","timestamp":1758823484175},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,11,2]],"date-time":"2014-11-02T00:00:00Z","timestamp":1414886400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Otto Kranendonk Fund of the Netherlands Society for Tropical Medicine"},{"name":"International Health and Dr\u00e4ger Medical South Africa (Pty) Ltd"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate safety and haematological effects of delayed cord clamping (<jats:styled-content style=\"fixed-case\">DCC<\/jats:styled-content>) in infants with expected low birthweight born in a resource\u2010poor setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Randomised controlled trial involving pregnant women in early labour \u226518\u00a0years with intrapartum symphysal\u2010fundal height \u226432\u00a0cm. Mothers were randomised for either early cord clamping (<jats:styled-content style=\"fixed-case\">ECC<\/jats:styled-content>, &lt;30\u00a0s) or <jats:styled-content style=\"fixed-case\">DCC<\/jats:styled-content> (2\u20133\u00a0min after birth).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included 104 vigorous infants born by vaginal delivery, of whom 39% had a birthweight &lt;2500\u00a0g. Infant haemoglobin (Hb) levels 24\u00a0h after birth were significantly higher in the DCC group (18.0\u00a0g\/dl vs 16.8\u00a0g\/dl, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.006). Despite successful placental transfusion, hyperbilirubinemia and hyperviscosity were not observed. Two months after birth, there were no differences in Hb between groups (9.9\u00a0g\/dl vs 9.8\u00a0g\/dl, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.60), but the infants in the DCC group had better weight gain from baseline than those with ECC (2.2\u00a0kg vs 1.9\u00a0kg, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.058).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this South African cohort of newborns with a subnormal distribution of birthweight delayed cord clamping was a safe procedure. Two months after birth the effect of <jats:styled-content style=\"fixed-case\">DCC<\/jats:styled-content> on Hb was not detectable anymore. <jats:styled-content style=\"fixed-case\">DCC<\/jats:styled-content> should be promoted in every singleton delivery in a resource\u2010poor setting irrespective of the birthweight.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.12419","type":"journal-article","created":{"date-parts":[[2014,10,20]],"date-time":"2014-10-20T03:51:59Z","timestamp":1413777119000},"page":"177-183","source":"Crossref","is-referenced-by-count":14,"title":["Delayed cord clamping in South African neonates with expected low birthweight: a randomised controlled trial"],"prefix":"10.1111","volume":"20","author":[{"given":"Sybrich","family":"Tiemersma","sequence":"first","affiliation":[{"name":"Department of Paediatrics University of Groningen Groningen The Netherlands"},{"name":"Department of Paediatrics Stanger Hospital KwaZulu\u2010Natal South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Heistein","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Groningen Groningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roos","family":"Ruijne","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Groningen Groningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo","family":"Lopez","sequence":"additional","affiliation":[{"name":"Medical Services Stanger Hospital KwaZulu\u2010Natal South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeroen","family":"van Lobenstein","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Stanger Hospital KwaZulu\u2010Natal South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"van Rheenen","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Groningen Groningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,11,2]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"The WHO Reproductive Health Library","author":"Abalos E","year":"2009"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d7157"},{"key":"e_1_2_7_4_1","first-page":"547","article-title":"Effect of delayed vs early cord clamping on iron status and neurodevelopment at age 12\u00a0months: a randomized clinical trial","volume":"168","author":"Andersson O","year":"2014","journal-title":"Journal of the American Medical Association Pediatrics"},{"key":"e_1_2_7_5_1","first-page":"322","article-title":"Effect of a two\u2010component intervention to change hospital practice from early to delayed umbilical cord clamping in the Peruvian Amazon","volume":"29","author":"Blouin B","year":"2011","journal-title":"Pan American Journal of Public Health"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2307\/3583242"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/02724936.1992.11747589"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/131.2.636S"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68889-2"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/33.1.86"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2393-10-23"},{"key":"e_1_2_7_12_1","first-page":"130","article-title":"Effect of delayed cord clamping on iron stores in infants born to anemic mothers: a randomized controlled trial","volume":"39","author":"Gupta R","year":"2002","journal-title":"Indian Pediatrics"},{"key":"e_1_2_7_13_1","first-page":"819","article-title":"Phototherapy and exchange transfusion for neonatal hyperbilirubinaemia. 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