{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T16:30:24Z","timestamp":1773765024936,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,5,26]],"date-time":"2015-05-26T00:00:00Z","timestamp":1432598400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000374","name":"British Medical Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000374","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the contribution of neurocysticercosis (<jats:styled-content style=\"fixed-case\">NCC<\/jats:styled-content>) to the burden of epilepsy in a rural Tanzanian population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We identified adult people with epilepsy (<jats:styled-content style=\"fixed-case\">PWE<\/jats:styled-content>) in a door\u2010to\u2010door study in an established demographic surveillance site. <jats:styled-content style=\"fixed-case\">PWE<\/jats:styled-content> and community controls were tested for antibodies to <jats:italic>Taenia solium,<\/jats:italic> the causative agent of <jats:styled-content style=\"fixed-case\">NCC<\/jats:styled-content>, and all <jats:styled-content style=\"fixed-case\">PWE<\/jats:styled-content> were offered a computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) head scan. Data on household occupancy and sanitation, pig\u2010keeping and pork consumption were collected from <jats:styled-content style=\"fixed-case\">PWE<\/jats:styled-content> and controls and associations with epilepsy were assessed using chi\u2010square or Fisher's exact tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Six of 218 <jats:styled-content style=\"fixed-case\">PWE<\/jats:styled-content> had antibodies to <jats:italic>T.\u00a0solium<\/jats:italic> (2.8%; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.6\u20134.9), compared to none of 174 controls (Fisher's exact test, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.04). Lesions compatible with <jats:styled-content style=\"fixed-case\">NCC<\/jats:styled-content> were seen in eight of 200 <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> scans (4.0%; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.3\u20136.7). A total of 176 <jats:styled-content style=\"fixed-case\">PWE<\/jats:styled-content> had both investigations of whom two had positive serology along with <jats:styled-content style=\"fixed-case\">NCC<\/jats:styled-content>\u2010compatible lesions on <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> (1.1%; 95% 0.3\u20134.0). No associations between epilepsy and any risk factors for <jats:styled-content style=\"fixed-case\">NCC<\/jats:styled-content> were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Neurocysticercosis is present in this population but at a lower prevalence than elsewhere in Tanzania and sub\u2010Saharan Africa. Insights from low\u2010prevalence areas may inform public health interventions designed to reduce the burden of preventable epilepsy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.12529","type":"journal-article","created":{"date-parts":[[2015,5,5]],"date-time":"2015-05-05T05:33:59Z","timestamp":1430804039000},"page":"1171-1179","source":"Crossref","is-referenced-by-count":18,"title":["Cysticercosis and epilepsy in rural Tanzania: a community\u2010based case\u2013control and imaging study"],"prefix":"10.1111","volume":"20","author":[{"given":"Ewan","family":"Hunter","sequence":"first","affiliation":[{"name":"Clinical Research Department Faculty of Infectious and Tropical Diseases London School of Hygiene and Tropical Medicine London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn","family":"Burton","sequence":"additional","affiliation":[{"name":"Cambridge University Hospitals NHS Foundation Trust Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Iqbal","sequence":"additional","affiliation":[{"name":"Institute of Neurosciences Southern General Hospital Glasgow UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Birchall","sequence":"additional","affiliation":[{"name":"Newcastle Hospitals NHS Foundation Trust Newcastle\u2010upon\u2010Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Jackson","sequence":"additional","affiliation":[{"name":"Newcastle Hospitals NHS Foundation Trust Newcastle\u2010upon\u2010Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane","family":"Rogathe","sequence":"additional","affiliation":[{"name":"Kilimanjaro Christian Medical Centre Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Jusabani","sequence":"additional","affiliation":[{"name":"Kilimanjaro Christian Medical Centre Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Gray","sequence":"additional","affiliation":[{"name":"Northumbria Healthcare NHS Foundation Trust North Shields UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Aris","sequence":"additional","affiliation":[{"name":"Muhimbili National Hospital Dar es Salaam Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gathoni","family":"Kamuyu","sequence":"additional","affiliation":[{"name":"Centre for Geographical Medicine (Coast) Kilifi Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia P.","family":"Wilkins","sequence":"additional","affiliation":[{"name":"Centers for Disease Control &amp; Prevention Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles R.","family":"Newton","sequence":"additional","affiliation":[{"name":"Centre for Geographical Medicine (Coast) Kilifi Kenya"},{"name":"Muhimbili\u2010Wellcome Programme Muhimbili University of Health and Allied Sciences Dar\u2010es\u2010Salaam Tanzania"},{"name":"Department of Psychiatry University of Oxford Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Walker","sequence":"additional","affiliation":[{"name":"Northumbria Healthcare NHS Foundation Trust North Shields UK"},{"name":"Institute of Health and Society Newcastle University Newcastle\u2010upon\u2010Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,5,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-009-1242-3"},{"key":"e_1_2_7_3_1","unstructured":"World Health Organisation.The Control of Neglected Zoonotic Diseases 2006. 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