{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:00:37Z","timestamp":1791270037535,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["095778"],"award-info":[{"award-number":["095778"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2015,9]]},"abstract":"Abstract<\/jats:title>Objectives<\/jats:title>Recent reports suggest that Schistosoma<\/jats:italic> infection may increase the risk of acquiring human immunodeficiency virus (HIV<\/jats:styled-content>). We used data from a large cross\u2010sectional study to investigate whether Schistosoma mansoni<\/jats:italic> infection is associated with increased HIV<\/jats:styled-content> prevalence.<\/jats:p><\/jats:sec>Methods<\/jats:title>We conducted a household survey of residents in island fishing communities in Mukono district, Uganda, between October 2012 and July 2013. HIV<\/jats:styled-content> status was assessed using rapid test kits. Kato\u2010Katz (KK<\/jats:styled-content>) stool tests and urine\u2010circulating cathodic antigen (CCA<\/jats:styled-content>) were used to test for Schistosoma<\/jats:italic> infection. Multivariable logistic regression, allowing for the survey design, was used to investigate the association between S.\u00a0mansoni<\/jats:italic> infection and HIV<\/jats:styled-content> infection.<\/jats:p><\/jats:sec>Results<\/jats:title>Data from 1412 participants aged 13\u00a0years and older were analysed (mean age 30.3\u00a0years, 45% female). The prevalence of HIV<\/jats:styled-content> was 17.3%. Using the stool Kato\u2010Katz technique on a single sample, S.\u00a0mansoni<\/jats:italic> infection was detected in 57.2% (719\/1257) of participants; urine CCA<\/jats:styled-content> was positive in 73.8% (478\/650) of those tested. S.\u00a0mansoni<\/jats:italic> infection was not associated with HIV<\/jats:styled-content> infection. [KK<\/jats:styled-content> (aOR<\/jats:styled-content>\u00a0=\u00a01.04; 95% CI<\/jats:styled-content>: 0.74\u20131.47, P<\/jats:italic>\u00a0=\u00a00.81), CCA<\/jats:styled-content> (aOR<\/jats:styled-content>\u00a0=\u00a01.53; 95% CI<\/jats:styled-content>: 0.78\u20133.00, P<\/jats:italic>\u00a0=\u00a00.19)]. The median S.\u00a0mansoni<\/jats:italic> egg count per gram was lower in the HIV<\/jats:styled-content>\u2010positive participants (P<\/jats:italic>\u00a0=\u00a00.005).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>These results add to the evidence that S.\u00a0mansoni<\/jats:italic> has little effect on HIV<\/jats:styled-content> transmission, but may influence egg excretion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.12545","type":"journal-article","created":{"date-parts":[[2015,5,15]],"date-time":"2015-05-15T11:38:26Z","timestamp":1431689906000},"page":"1201-1208","source":"Crossref","is-referenced-by-count":34,"title":["Schistosoma mansoni<\/i> and HIV<\/scp> infection in a Ugandan population with high HIV<\/scp> and helminth prevalence"],"prefix":"10.1111","volume":"20","author":[{"given":"Richard E.","family":"Sanya","sequence":"first","affiliation":[{"name":"Medical Research Council\/UVRI Uganda Research Unit on AIDS Entebbe Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence","family":"Muhangi","sequence":"additional","affiliation":[{"name":"Medical Research Council\/UVRI Uganda Research Unit on AIDS Entebbe Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Nampijja","sequence":"additional","affiliation":[{"name":"Medical Research Council\/UVRI Uganda Research Unit on AIDS Entebbe Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Nannozi","sequence":"additional","affiliation":[{"name":"Makerere University Joint AIDS Programme Kampala Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prossy Kabuubi","family":"Nakawungu","sequence":"additional","affiliation":[{"name":"Medical Research Council\/UVRI Uganda Research Unit on AIDS Entebbe Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elson","family":"Abayo","sequence":"additional","affiliation":[{"name":"Entebbe General Hospital Entebbe Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily L.","family":"Webb","sequence":"additional","affiliation":[{"name":"London School of Hygiene & Tropical Medicine London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison M.","family":"Elliott","sequence":"additional","affiliation":[{"name":"Medical Research Council\/UVRI Uganda Research Unit on AIDS Entebbe Uganda"},{"name":"London School of Hygiene & Tropical Medicine London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the LaVIISWA study team","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,6]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Schistosomiais Fact Sheet Number 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