{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T20:33:23Z","timestamp":1773866003749,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T00:00:00Z","timestamp":1488412800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000889","name":"Multiple Sclerosis Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000889","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>As neonatal care is being scaled up in economically poor settings, there is a need to know more on post\u2010hospital discharge and longer\u2010term outcomes. Of particular interest are mortality, prevalence of developmental impairments and malnutrition, all known to be worse in low\u2010birthweight neonates (<jats:styled-content style=\"fixed-case\">LBW<\/jats:styled-content>, &lt;2500 g). Getting a better handle on these parameters might justify and guide support interventions. Two years after hospital discharge, we thus assessed: mortality, developmental impairments and nutritional status of <jats:styled-content style=\"fixed-case\">LBW<\/jats:styled-content> children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Household survey of <jats:styled-content style=\"fixed-case\">LBW<\/jats:styled-content> neonates discharged from a neonatal special care unit in Rural Burundi between January and December 2012.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 146 <jats:styled-content style=\"fixed-case\">LBW<\/jats:styled-content> neonates, 23% could not be traced and 4% had died. Of the remaining 107 children (median age = 27 months), at least one developmental impairment was found in 27%, with 8% having at least five impairments. Main impairments included delays in motor development (17%) and in learning and speech (12%). Compared to <jats:styled-content style=\"fixed-case\">LBW<\/jats:styled-content> children (<jats:italic>n<\/jats:italic> = 100), very\u2010low\u2010birthweight (<jats:styled-content style=\"fixed-case\">VLBW<\/jats:styled-content>, &lt;1500 g, <jats:italic>n<\/jats:italic> = 7) children had a significantly higher risk of impairments (intellectual \u2013 <jats:italic>P<\/jats:italic> = 0.001), needing constant supervision and creating a household burden (<jats:italic>P<\/jats:italic> = 0.009). Of all children (<jats:italic>n<\/jats:italic>\u2010107), 18% were acutely malnourished, with a 3\u00bd times higher risk in <jats:styled-content style=\"fixed-case\">VLBW<\/jats:styled-content>s (<jats:italic>P<\/jats:italic> = 0.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Reassuringly, most children were thriving 2 years after discharge. However, malnutrition was prevalent and one in three manifested developmental impairments (particularly <jats:styled-content style=\"fixed-case\">VLBW<\/jats:styled-content>s) echoing the need for support programmes. A considerable proportion of children could not be traced, and this emphasises the need for follow\u2010up systems post\u2010discharge.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.12845","type":"journal-article","created":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:42:47Z","timestamp":1485909767000},"page":"423-430","source":"Crossref","is-referenced-by-count":11,"title":["How do low\u2010birthweight neonates fare 2 years after discharge from a low\u2010technology neonatal care unit in a rural district hospital in Burundi?"],"prefix":"10.1111","volume":"22","author":[{"given":"W.","family":"van den Boogaard","sequence":"first","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res Brussels Operational Centre \u2013 Operational Research Unit (LuxOR) Luxembourg City Luxembourg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Zuniga","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res Brussels Operational Centre Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Manzi","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res Brussels Operational Centre \u2013 Operational Research Unit (LuxOR) Luxembourg City Luxembourg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Van den Bergh","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res Brussels Operational Centre \u2013 Operational Research Unit (LuxOR) Luxembourg City Luxembourg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Lefevre","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res Brussels Operational Centre Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Nanan\u2010N'zeth","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res Bujumbura Burundi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Duchenne","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res Bujumbura Burundi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Etienne","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res Brussels Operational Centre Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Juma","sequence":"additional","affiliation":[{"name":"Ministry of Health Bujumbura Burundi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Ndelema","sequence":"additional","affiliation":[{"name":"Ministry of Health Bujumbura Burundi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Zachariah","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res Brussels Operational Centre \u2013 Operational Research Unit (LuxOR) Luxembourg City Luxembourg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Reid","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res Brussels Operational Centre \u2013 Operational Research Unit (LuxOR) Luxembourg City Luxembourg"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,2]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"The World Bank Group.Mortality rate neonatal (per 1 000 live births) 2014. 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