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We reviewed articles on sub\u2010Saharan African people living with <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">PLHIV<\/jats:styled-content>) &gt;18 years old, published until November 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 537 articles, 12 were conducted in six African countries and included in this review. Five articles reported information on functional limitation and one on disability. Two of these five articles reported functional limitation (low gait speed) in <jats:styled-content style=\"fixed-case\">PLHIV<\/jats:styled-content>. Disability was observed in 27% and 3% of <jats:styled-content style=\"fixed-case\">PLHIV<\/jats:styled-content> living in rural and urban places, respectively. Two of three studies reporting grip strength reported lower grip strength (nearly 4 kg) in <jats:styled-content style=\"fixed-case\">PLHIV<\/jats:styled-content> in comparison with uninfected patients. One study reported that <jats:styled-content style=\"fixed-case\">PLHIV<\/jats:styled-content> were more likely to be frail than <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010uninfected individuals (19.4% <jats:italic>vs<\/jats:italic>. 13.3%), whereas another reported no statistical difference.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Decline in physical function, grip strength and frailty are now part of the burden of <jats:styled-content style=\"fixed-case\">PLHIV<\/jats:styled-content> living in <jats:styled-content style=\"fixed-case\">SSA<\/jats:styled-content> countries, but current data are insufficient to characterise the real public health dimension of these impairments. Further studies are needed to depict this major public health challenge. As this is likely to contribute to a significant burden on the African healthcare systems and human resources in the near future, a holistic care approach should be developed to inform guidelines.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.12852","type":"journal-article","created":{"date-parts":[[2017,2,7]],"date-time":"2017-02-07T13:56:42Z","timestamp":1486475802000},"page":"516-525","source":"Crossref","is-referenced-by-count":31,"title":["Physical function, grip strength and frailty in people living with <scp>HIV<\/scp> in sub\u2010Saharan Africa: systematic review"],"prefix":"10.1111","volume":"22","author":[{"given":"Charlotte","family":"Bernard","sequence":"first","affiliation":[{"name":"INSERM Centre INSERM U1219 Bordeaux Population Health Bordeaux France"},{"name":"School of Public Health (ISPED) University of Bordeaux Bordeaux 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