{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T14:26:36Z","timestamp":1782570396883,"version":"3.54.5"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,3,27]],"date-time":"2019-03-27T00:00:00Z","timestamp":1553644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>[<jats:sup>18<\/jats:sup>F]\u20102\u2010fluoro\u20102\u2010deoxy\u2010D\u2010glucose (18F\u2010<jats:styled-content style=\"fixed-case\">FDG<\/jats:styled-content>) positron emission tomography\/computed tomography (<jats:styled-content style=\"fixed-case\">FDG<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) imaging provides important information about the size and metabolic activity of lesions caused by <jats:italic>Echinococcus multilocularis<\/jats:italic> and is therefore recommended for the initial assessment and follow\u2010up of human alveolar echinococcosis (<jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content>). The introduction of positron emission tomography\/magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>) into clinical practice in affluent health care systems provides an alternative dual imaging modality, which has not yet been evaluated for <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>Here, we describe the initial clinical experience with comparative <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> imaging in four human <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content> patients at an Austrian reference centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> imaging showed comparable diagnostic capacity for liver lesions attributable to <jats:italic>E.\u00a0multilocularis<\/jats:italic> infection, with a discrepancy only in the assessment of calcifications in one patient. Effective doses of radiation were 30.4\u201331\u00a0m<jats:styled-content style=\"fixed-case\">SV<\/jats:styled-content> for <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>, which were reduced in <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> to the exposure of <jats:sup>18<\/jats:sup>F\u2010<jats:styled-content style=\"fixed-case\">FDG<\/jats:styled-content> only (4.9\u20135.5\u00a0mSv).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> provides comparable diagnostic information for <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content> management. The reduction in radiation exposure compared to <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> may be of particular importance for children and young patients not amenable for curative surgery requiring repeated long\u2010term follow\u2010up with dual imaging modalities. Further studies are warranted to prospectively evaluate the potential of <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> in the management of <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.13228","type":"journal-article","created":{"date-parts":[[2019,3,9]],"date-time":"2019-03-09T20:18:30Z","timestamp":1552162710000},"page":"663-670","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["<scp>FDG<\/scp>\u2010<scp>PET<\/scp>\/<scp>MRI<\/scp> imaging for the management of alveolar echinococcosis: initial clinical experience at a reference centre in Austria"],"prefix":"10.1111","volume":"24","author":[{"given":"Felix","family":"L\u00f6tsch","sequence":"first","affiliation":[{"name":"Department of Medicine I Division of Infectious Diseases and Tropical Medicine Medical University of Vienna Vienna Austria"},{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fredrik","family":"Waneck","sequence":"additional","affiliation":[{"name":"Department of Biomedical Imaging and Image\u2010guided Therapy Division of Radiology Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirjam","family":"Groger","sequence":"additional","affiliation":[{"name":"Department of Medicine I Division of Infectious Diseases and Tropical Medicine Medical University of Vienna Vienna Austria"},{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert","family":"Auer","sequence":"additional","affiliation":[{"name":"Department of Medical Parasitology Institute of Specific Prophylaxis and Tropical Medicine Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Kaczirek","sequence":"additional","affiliation":[{"name":"Department of Surgery Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivo","family":"Rausch","sequence":"additional","affiliation":[{"name":"Center for Medical Physics Biomedical Engineering Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Wadsak","sequence":"additional","affiliation":[{"name":"Department of Biomedical Imaging and Image\u2010guided Therapy Division of Nuclear Medicine Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Hacker","sequence":"additional","affiliation":[{"name":"Department of Biomedical Imaging and Image\u2010guided Therapy Division of Nuclear Medicine Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heimo","family":"Lagler","sequence":"additional","affiliation":[{"name":"Department of Medicine I Division of Infectious Diseases and Tropical Medicine Medical University of Vienna Vienna Austria"},{"name":"Institut f\u00fcr Tropenmedizin University of T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ramharter","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"},{"name":"Department of Tropical Medicine Bernhard Nocht Institute for Tropical Medicine &amp; I. 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