{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T13:54:16Z","timestamp":1789826056380,"version":"4.0.1"},"reference-count":18,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,6,11]],"date-time":"2020-06-11T00:00:00Z","timestamp":1591833600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To date, the burden of childhood spinal TB in China has not been estimated, and current treatment is hindered by a lack of evidence. This study aimed to review our experience of childhood spinal TB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed the medical records of paediatric patients (\u226415\u00a0years) admitted for spinal TB (confirmed or possible) at Shandong Provincial Chest Hospital from January 2006 to December 2019. Demographic, clinical, laboratory and radiological data were collected from medical records and analysed retrospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010two patients were diagnosed with spinal TB. 45 were male (62.5%), and 27 female (37.5%), with a mean age of 8.42\u00a0\u00b1\u00a04.47 (SD) years. During this 14\u2010year period, the overall prevalence of spinal TB among childhood TB was 4.5%. T\u2010SPOT.TB, AFB smear, mycobacterial culture, TB RT\u2010PCR and biopsies were positive in 29.6%, 14.3%, 23.3%, 43.8% and 88.5% of assayed patients, respectively. The overall surgical rate of the studied patients was 40.3%. The requirement of surgery in childhood spinal TB was associated with pulmonary TB (OR\u00a0=\u00a04.000, 95% CI: 1.197, 13.367).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Spinal TB in children cannot be neglected. It remains a severe problem to public health, and more attention should be paid to initiating treatment early.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.13411","type":"journal-article","created":{"date-parts":[[2020,5,2]],"date-time":"2020-05-02T05:22:19Z","timestamp":1588396939000},"page":"834-838","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The prevalence, diagnosis and surgical risk factors of spinal tuberculosis in children"],"prefix":"10.1111","volume":"25","author":[{"given":"Mao\u2010Shui","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Lab Medicine Shandong Provincial Chest Hospital, Cheeloo College of Medicine Shandong University Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Geriatrics Shandong Mental Health Center Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun\u2010Li","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Lab Medicine The Affiliated Hospital of Youjiang Medical University for Nationalities Baise China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng\u2010Lin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Shandong Provincial Chest Hospital, Cheeloo College of Medicine Shandong University Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,11]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"WHO.Global tuberculosis report 2019.World Health Organization:Geneva;2019."},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.RVW.M.00130"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.4184\/asj.2017.11.3.405"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00011973"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268818002649"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-011-1469-2"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.4184\/asj.2016.10.3.543"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300060519869715"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2011-301571"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-017-2447-0"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcy167"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2005.032862"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/2152-7806.75459"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-012-2336-6"},{"key":"e_1_2_6_16_1","first-page":"773","article-title":"The natural history of idiopathic scoliosis before skeletal maturity","volume":"1986","author":"Bunnell WP","year":"1976","journal-title":"Spine (Phila Pa"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.76B6.7983109"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199910000-00002"},{"key":"e_1_2_6_19_1","first-page":"9765253","article-title":"Clinical characteristics of 1378 inpatients with spinal tuberculosis in general Hospitals in South\u2010Central China","volume":"2019","author":"Liu Z","year":"2019","journal-title":"Biomed Res Int"}],"container-title":["Tropical Medicine &amp; International Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tmi.13411","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tmi.13411","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tmi.13411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T01:54:46Z","timestamp":1693965286000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tmi.13411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,11]]},"references-count":18,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1111\/tmi.13411"],"URL":"https:\/\/doi.org\/10.1111\/tmi.13411","archive":["Portico"],"relation":{},"ISSN":["1360-2276","1365-3156"],"issn-type":[{"value":"1360-2276","type":"print"},{"value":"1365-3156","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,11]]},"assertion":[{"value":"2020-06-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}