{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T19:51:53Z","timestamp":1792007513803,"version":"4.4.0"},"reference-count":43,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,12,20]],"date-time":"2020-12-20T00:00:00Z","timestamp":1608422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["71964021"],"award-info":[{"award-number":["71964021"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the prevalence of <jats:italic>Helicobacter pylori<\/jats:italic> infection and risk factors and to serotype the strains in Wuwei, located in north\u2010western China, which has a high incidence of gastric cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:italic>Helicobacter pylori<\/jats:italic> infection was analysed in 21\u00a0291 adults by <jats:sup>14<\/jats:sup>C\u2010urea breath test, and <jats:italic>H.\u00a0pylori<\/jats:italic> antibody were detected in 9183 serum samples by latex immunoturbidimetric method. The correlation of <jats:italic>H.\u00a0pylori<\/jats:italic> infection with demographic\u2013economic, lifestyle factors and medical history among the participants was determined by questionnaire. The antibodies against <jats:italic>H.\u00a0pylori<\/jats:italic> urease, VacA and CagA in serum were determined by dot immunobinding assay.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The infection rate of <jats:italic>H.\u00a0pylori<\/jats:italic> was 53.0%, and 90.1% of strains were type I strains. The <jats:italic>H.\u00a0pylori<\/jats:italic> infection rate was higher among farmers (OR\u00a0=\u00a01.34, 95% CI: 1.19\u20131.50) and individuals who had a junior high school or higher education level (OR\u00a0=\u00a01.10, 95% CI: 1.06\u20131.15), and was lower in older individuals (OR\u00a0=\u00a00.86, 95% CI: 0.83\u20130.90), individuals with high income (OR\u00a0=\u00a00.93, 95% CI: 0.90\u20130.95), individuals with a habit of eating quickly (OR\u00a0=\u00a00.93, 95% CI: 0.87\u20130.99) and individuals who consumed more fruit and vegetables (OR\u00a0=\u00a00.90, 95% CI: 0.85\u20130.95). Individuals with history of cholecystitis\/cholecystolithiasis, hypertension and asthma were negatively correlated with <jats:italic>H.\u00a0pylori<\/jats:italic> infection (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The prevalence of <jats:italic>H.\u00a0pylori<\/jats:italic> infection is high in Wuwei. The major prevalent strain is type I strain. Age, education, occupation, household income, consumption of fruit and vegetables, and habit of eating quickly are independent risk factors for <jats:italic>H.\u00a0pylori<\/jats:italic> infection, which is also associated with individuals with a history of extragastric diseases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.13517","type":"journal-article","created":{"date-parts":[[2020,11,7]],"date-time":"2020-11-07T17:47:29Z","timestamp":1604771249000},"page":"290-300","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Prevalence and associated risk factors of <i>Helicobacter pylori<\/i> infection in the Wuwei cohort of north\u2010western China"],"prefix":"10.1111","volume":"26","author":[{"given":"Fuhua","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Gastroenterology First Hospital of Lanzhou University Lanzhou China"},{"name":"Key Laboratory for Gastrointestinal Diseases, Gansu Province 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