{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:39:08Z","timestamp":1762508348775},"reference-count":54,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T00:00:00Z","timestamp":1610928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe the clinical and sociodemographic characteristics of participants as well as discontinuation and mortality rates in a cardiac rehabilitation programme (CRP) tailored to Chagas disease (CD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants underwent functional capacity, anthropometry and cardiac function evaluations before beginning a CRP. Univariate and multivariate Cox proportional hazards models were performed to investigate the associations between clinical and sociodemographic characteristics at baseline with discontinuation rates and deaths.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010two patients were enrolled in the CRP (61.9% men, mean age of 58.1\u00a0\u00b1\u00a011.8\u00a0years). During a median follow\u2010up period of 10.8\u00a0months, 74% discontinued and 14% died while enrolled in CRP. 34% of the patients who discontinued CRP died during follow\u2010up. White race (HR\u00a0=\u00a00.09; 95% CI 0.01\u20131.00), right ventricular systolic dysfunction (HR\u00a0=\u00a010.54; 95% CI 1.24\u201389.50) and oxygen pulse (HR\u00a0=\u00a00.69; 95% CI 0.48\u20130.99) were independently associated with death while enrolled in CRP. Married status (HR\u00a0=\u00a00.44; 95% CI 0.21\u20130.95) was independently associated with discontinuation rates from CRP. VO<jats:sub>2<\/jats:sub> peak (HR\u00a0=\u00a00.85; 95% CI 0.74\u20130.98) and CRP discontinuation due to CD\u2010related reasons (HR\u00a0=\u00a08.33; 95% CI 1.91\u201336.27) were the variables independently associated with death after discontinuation of CRP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this population, sociodemographic aspects and severity of CD were important determinants of CRP discontinuation and mortality.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.13537","type":"journal-article","created":{"date-parts":[[2020,12,11]],"date-time":"2020-12-11T09:01:27Z","timestamp":1607677287000},"page":"355-365","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Factors related to the discontinuation and mortality rates of a cardiac rehabilitation programme in patients with Chagas disease: a 6\u2010year experience in a Brazilian tertiary 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