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For RSV\u2010positive samples, sequence analysis of the second hypervariable region of the G gene was performed. A dataset of RSV strains from sub\u2010Saharan Africa (2011\u20132017) currently available in GenBank was compiled. Phylogenetic analysis was conducted to identify the diversity of circulating RSV genotypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 46 samples were tested RSV positive (Ghana <jats:italic>n<\/jats:italic>\u00a0=\u00a031 (6.3%), Gabon <jats:italic>n<\/jats:italic>\u00a0=\u00a04 (2.2%), Tanzania <jats:italic>n<\/jats:italic>\u00a0=\u00a09 (3.1%) and Burkina Faso <jats:italic>n<\/jats:italic>\u00a0=\u00a02 (1.7%)). The most common RSV co\u2010infection was with rhinovirus. All RSV A strains clustered with genotype ON1 strains with a 72\u2010nucleotide duplication and all RSV B strains belonged to genotype BAIX. Phylogenetic analysis of amino acid sequences from sub\u2010Saharan Africa revealed the diversification into 11 different ON1 and 22 different BAIX lineages and differentiation of ON1 and BAIX strains into potential new sub\u2010genotypes, provisionally named ON1\u2010NGR, BAIX\u2010KEN1, BAIX\u2010KEN2 and BAIX\u2010KEN3.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The study contributes to an improved understanding of the molecular epidemiology of RSV infection in sub\u2010Saharan Africa. It provides the first phylogenetic data for RSV from Tanzania, Gabon and Burkina Faso and combines it with RSV strains from all other sub\u2010Saharan countries currently available in GenBank.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.13573","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T16:53:05Z","timestamp":1615222385000},"page":"810-822","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Molecular epidemiology of respiratory syncytial virus in children in sub\u2010Saharan Africa"],"prefix":"10.1111","volume":"26","author":[{"given":"Clara Marlene","family":"Ihling","sequence":"first","affiliation":[{"name":"Center of Infectious Diseases Virology Heidelberg University Hospital Heidelberg Germany"},{"name":"German Center for Infection Research (DZIF) Heidelberg Germany"},{"name":"Dr. von Haunersches Kinderspital University Hospital of the LMU Munich Munich 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