{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T23:33:35Z","timestamp":1788910415423,"version":"build-2803163510"},"reference-count":35,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T00:00:00Z","timestamp":1620086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To report the prevalence of polyparasitism during pregnancy in the Lambar\u00e9n\u00e9 region of Gabon and its association with newborn birth weight.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Pregnant women in their third trimester were recruited in a prospective study between November 2011 and March 2015. Parasite infection status was assessed microscopically in stool, urine and blood samples. Maternal demographic and obstetrical characteristics and newborns anthropometric data were collected. Multivariable logistic regression was used to assess the association between low birth weight and polyparasitism.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      678 of 927 pregnant women were included for analysis with mean age (SD) of 25 (6.8) years. The analysis showed that 69% (468\/678) were infected with at least one parasite (\n                      <jats:italic>Plasmodium spp<\/jats:italic>\n                      .,\n                      <jats:italic>Schistosoma spp<\/jats:italic>\n                      ., soil\u2010transmitted helminths, filarial infections). This comprised of 38% with monoparasitism and 31% polyparasitism. The proportion of newborn babies with a weight below 2500\u00a0g (LBW) in our study was 21% (142\/678). Compared to pregnant women without infection, women with monoparasitic infection had adjusted Odds Ratio confidence interval 95% CI (aOR [95%CI]) of 1.6 [0.95\u20132.73], those with two parasites had aOR 95%CI of 2.63 [1.51\u20134.62], and those with more than two parasites had aOR of 5.08 [2.5\u201310.38] for delivering a newborn with low birth weight.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In Lambar\u00e9n\u00e9, an endemic area for multiple parasite infections, there is a high prevalence of polyparasitism in pregnant women. Polyparasitism is associated with low birth weight. Therefore, there is an urgent need for active screening and treatment of parasite infections in pregnant women to assess the potential public health benefit of such interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/tmi.13591","type":"journal-article","created":{"date-parts":[[2021,4,16]],"date-time":"2021-04-16T16:39:13Z","timestamp":1618591153000},"page":"973-981","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Association of low birth weight and polyparasitic infection during pregnancy in Lambar\u00e9n\u00e9, Gabon"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9726-6643","authenticated-orcid":false,"given":"Yabo Josiane","family":"Honkp\u00e9h\u00e8dji","sequence":"first","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"},{"name":"Department of Parasitology Leiden University Medical Center Leiden The Netherlands"},{"name":"Institut f\u00fcr Tropenmedizin Eberhard\u2010Karls\u2010Universit\u00e4t T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bayode Romeo","family":"Adegbite","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"},{"name":"Institut f\u00fcr Tropenmedizin Eberhard\u2010Karls\u2010Universit\u00e4t T\u00fcbingen T\u00fcbingen Germany"},{"name":"Center of Tropical Medicine and Travel Medicine University of Amsterdam Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeannot Fr\u00e9jus","family":"Zinsou","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"},{"name":"Department of Parasitology Leiden University Medical Center Leiden The Netherlands"},{"name":"Institut f\u00fcr Tropenmedizin Eberhard\u2010Karls\u2010Universit\u00e4t T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Claude","family":"Dejon\u2010Agob\u00e9","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"},{"name":"Institut f\u00fcr Tropenmedizin Eberhard\u2010Karls\u2010Universit\u00e4t T\u00fcbingen T\u00fcbingen Germany"},{"name":"Center of Tropical Medicine and Travel Medicine University of Amsterdam Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Ronald","family":"Edoa","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rella","family":"Zoleko Manego","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"},{"name":"Institut f\u00fcr Tropenmedizin Eberhard\u2010Karls\u2010Universit\u00e4t T\u00fcbingen T\u00fcbingen Germany"},{"name":"Department of Tropical Medicine Bernhard Nocht Institute for Tropical Medicine Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"McCall","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"},{"name":"Institut f\u00fcr Tropenmedizin Eberhard\u2010Karls\u2010Universit\u00e4t T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirabeau","family":"Mbong Ngwese","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrice","family":"Lotola Mougeni","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghyslain","family":"Mombo\u2010Ngoma","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"},{"name":"Institut f\u00fcr Tropenmedizin Eberhard\u2010Karls\u2010Universit\u00e4t T\u00fcbingen T\u00fcbingen Germany"},{"name":"Department of Tropical Medicine Bernhard Nocht Institute for Tropical Medicine Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ramharter","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"},{"name":"Department of Tropical Medicine Bernhard Nocht Institute for Tropical Medicine Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter G.","family":"Kremsner","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"},{"name":"Institut f\u00fcr Tropenmedizin Eberhard\u2010Karls\u2010Universit\u00e4t T\u00fcbingen T\u00fcbingen Germany"},{"name":"German Center for Infection Research T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Lell","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"},{"name":"Institut f\u00fcr Tropenmedizin Eberhard\u2010Karls\u2010Universit\u00e4t T\u00fcbingen T\u00fcbingen Germany"},{"name":"Division of Infectious Diseases and Tropical Medicine Department of Medicine I Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Yazdanbakhsh","sequence":"additional","affiliation":[{"name":"Department of Parasitology Leiden University Medical Center Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meral","family":"Esen","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"},{"name":"Institut f\u00fcr Tropenmedizin Eberhard\u2010Karls\u2010Universit\u00e4t T\u00fcbingen T\u00fcbingen Germany"},{"name":"German Center for Infection Research T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u00f4la Akim","family":"Adegnika","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 Lambar\u00e9n\u00e9 Gabon"},{"name":"Department of Parasitology Leiden University Medical Center Leiden The Netherlands"},{"name":"Institut f\u00fcr Tropenmedizin Eberhard\u2010Karls\u2010Universit\u00e4t T\u00fcbingen T\u00fcbingen Germany"},{"name":"German Center for Infection Research T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,4]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"WHO|WHO recommendations on antenatal care for a positive pregnancy experience[Internet]. WHO. World Health Organization; [cited 2020 Jul 24]. Available from:http:\/\/www.who.int\/reproductivehealth\/publications\/maternal_perinatal_health\/anc\u2010positive\u2010pregnancy\u2010experience\/en\/"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4135-8"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2007.77.88"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-016-1413-6"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(83)90081-0"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(07)70021-X"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2010.09-0165"},{"key":"e_1_2_10_9_1","unstructured":"WHO|Deworming in pregnant women[Internet]. WHO. World Health Organization; [cited 2020 Jul 24]. Available from:http:\/\/www.who.int\/elena\/titles\/deworming_pregnancy\/en\/"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2010.02598.x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2009.80.896"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(10)73002-5"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/6173465"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-6-263"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-017-4045-x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2105.141471"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2016.11.001"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-011783"},{"key":"e_1_2_10_19_1","unstructured":"Gabon \u2010 administrative boundaries \u2010 humanitarian data exchange[Internet]. [cited 2019 Dec 9]. Available from:https:\/\/data.humdata.org\/dataset\/gabon\u2010administrative\u2010boundaries"},{"key":"e_1_2_10_20_1","unstructured":"OpenStreetMap[Internet].OpenStreetMap. [cited 2019 Dec 9]. Available from:https:\/\/www.openstreetmap.org\/"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006663"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines8030381"},{"key":"e_1_2_10_23_1","unstructured":"Low birthweight: country regional and global estimates[Internet]. UNICEF. [cited 2020 Jul 24]. Available from:https:\/\/www.unicef.org\/publications\/index_24840.html#"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-13-234"},{"key":"e_1_2_10_25_1","first-page":"390","article-title":"Comparison of thick blood smear and saponin haemolysis for the detection of Loa loa and Mansonella perstans infections","volume":"93","author":"Noireau F","year":"1990","journal-title":"J Trop Med Hyg"},{"key":"e_1_2_10_26_1","unstructured":"Organization WH.Basic laboratory methods in medical parasitology[Internet]. World Health Organization; 1991 [cited 2020 May 13]. Available from:https:\/\/apps.who.int\/iris\/handle\/10665\/40793"},{"key":"e_1_2_10_27_1","unstructured":"WHO|Bench Aids for the diagnosis of intestinal parasites[Internet]. WHO. [cited 2019 Feb 25]. Available from:http:\/\/www.who.int\/intestinal_worms\/resources\/9789241544764\/en\/"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1991.45.518"},{"key":"e_1_2_10_29_1","unstructured":"Studies on the laboratory diagnosis of human filariasis: Preliminary communication[Internet]. [cited 2018 Sep 20]. Available from:https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC476852\/"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/2613484"},{"key":"e_1_2_10_32_1","unstructured":"Joseph: Malaria and geohelminths co infection in\u2026 \u2010 Google Scholar [Internet]. [cited 2020 Aug 5]. Available from: HYPERLINK \"sps:urlprefix::https\"https:\/\/scholar.google.com\/scholar_lookup?journal=Sokoto+Journal+of+Medical+Laboratory+Science&title=Malaria+and+geohelminths+co+infection+in+pregnancy+and+its+association+with+maternal+anaemia+and+birth+outcome+among+pregnant+women+attending+Federal+Medical+Centre+Yola+and+Specialist+Hospital&author=R.+Joseph&author=G.+Chessed&author=L.+Daniel&author=Y.+Haruna&author=M.+Demshemino&volume=1&publication_year=2016&pages=221\u2010227&doi=10.4314\/jasem.v21i3.7&"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2012.12-0371"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1155\/IDOG\/2006\/23125"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-016-2327-5"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2010.05.003"}],"container-title":["Tropical Medicine &amp; International Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tmi.13591","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tmi.13591","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tmi.13591","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T04:50:25Z","timestamp":1693198225000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tmi.13591"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,4]]},"references-count":35,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1111\/tmi.13591"],"URL":"https:\/\/doi.org\/10.1111\/tmi.13591","archive":["Portico"],"relation":{},"ISSN":["1360-2276","1365-3156"],"issn-type":[{"value":"1360-2276","type":"print"},{"value":"1365-3156","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,4]]},"assertion":[{"value":"2021-05-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}