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Biomarker\u2010based tests to diagnose incipient TB hold promise for better prediction and, through TB preventive therapy, prevention of disease. This study explored current and future framing and prioritisation of ITB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010two interviews across eight countries were conducted. A modified Shiffman &amp; Smith Framework, containing four categories\u2014Ideas, Issue Characteristics, Actor Power, and Political Contexts\u2014was used to analyse the current landscape and potential for prioritisation of diagnosis and treatment of ITB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Latent TB policy implementation has been slow due to technical, logistical and financial challenges, and because it has been framed in a manner non\u2010conducive to gaining political priority. Framing ITB testing as \u2018early detection\u2019 rather than \u2018prediction\u2019, and its management as \u2018treatment\u2019 rather than \u2018preventive therapy\u2019, may help raise its importance in policies, and its acceptance among actors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Consensus surrounding the framing of ITB will be crucial for the successful adoption of ITB diagnostics and treatment. When designing ITB tools and policies, it will be important to address challenges that pertain to latent TB policies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.13734","type":"journal-article","created":{"date-parts":[[2022,2,14]],"date-time":"2022-02-14T05:53:14Z","timestamp":1644817994000},"page":"445-453","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Framing the detection of incipient tuberculosis infection: A\u00a0qualitative study of political prioritisation"],"prefix":"10.1111","volume":"27","author":[{"given":"Rosemary","family":"James","sequence":"first","affiliation":[{"name":"Department of Health, Ethics &amp; Society Maastricht University  Maastricht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grant","family":"Theron","sequence":"additional","affiliation":[{"name":"Clinical Mycobacteriology and Epidemiology Group Stellenbosch University  Stellenbosch South 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