{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:32:39Z","timestamp":1787164359821,"version":"build-2736575974"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T00:00:00Z","timestamp":1700438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Isolated cases of subacute thyroiditis exist in the early period of COVID\u201019 vaccination, largely after mRNA vaccines. Here we report late onset thyroid disturbances and persistent health issues in patients of thyroid disorders after COVID\u201019 vaccination. Seventy\u2010five patients with post COVID\u201019 vaccination thyroid disturbances were identified. Among these, 41 had flare of underlying thyroid illness, majority occurring at a median time lag of 28.4\u2009weeks since 2nd dose. Thirty\u2010one cases of new onset hypothyroidism and three of new onset hyperthyroidism were reported, with a median time lag respectively of 17.2 and 22.6\u2009weeks since 2nd dose. Most cases occurred after ChAdOx1\u2010nCoV\u201019, which was the commonest vaccine employed in mass roll out in India. Significant improvement was observed in majority, after a median follow up of 22\u201326\u2009weeks. New onset health issues persisting for \u22654\u2009weeks were reported in 37.3% and were common in individuals with history of COVID\u201019 before vaccine. New onset metabolic, musculoskeletal, and reproductive disorders were the common health complaints. Active monitoring is warranted for late onset adverse events after COVID\u201019 vaccines of all types. Larger studies with involvement of unvaccinated individuals are required to understand the incidence and causality of late onset thyroid disturbances after COVID\u201019 vaccines.<\/jats:p>","DOI":"10.1111\/tmi.13947","type":"journal-article","created":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T08:05:57Z","timestamp":1700553957000},"page":"63-71","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Patterns and outcomes of late onset thyroid disturbances after\n                    <scp>COVID<\/scp>\n                    \u201019 vaccination: A report of 75 cases"],"prefix":"10.1111","volume":"29","author":[{"given":"Upinder","family":"Kaur","sequence":"first","affiliation":[{"name":"Department of Pharmacology, Institute of Medical Sciences Banaras Hindu University  Varanasi Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noti Taruni Srija","family":"Reddy","sequence":"additional","affiliation":[{"name":"Institute of Medical Sciences Banaras Hindu University  Varanasi Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaideep","family":"Reddy","sequence":"additional","affiliation":[{"name":"Institute of Medical Sciences Banaras Hindu University  Varanasi Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dondapati Venkata Vamshi","family":"Krishna","sequence":"additional","affiliation":[{"name":"Institute of Medical Sciences Banaras Hindu University  Varanasi Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amol","family":"Dehade","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Institute of Medical Sciences Banaras Hindu University  Varanasi Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neeraj Kumar","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, Institute of Medical Sciences Banaras Hindu University  Varanasi Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40336-021-00419-y"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2021.102312"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10071153"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.13443"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40618-022-01786-7"},{"key":"e_1_2_10_7_1","volume-title":"Endotext [Internet]","author":"Hennessey J","year":"2018"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40618-022-01747-0"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40618-021-01718-x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2023.101759"},{"key":"e_1_2_10_11_1","unstructured":"Our World in data.Coronavirus (COVID\u201019) Vaccinations. What\u2010share\u2010of\u2010the\u2010population\u2010has\u2010received\u2010at\u2010least\u2010one\u2010dose\u2010and\u2010completed\u2010the\u2010initial\u2010vaccination\u2010protocol.2023."},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/10815589231173876"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-023-01301-8"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1210\/endocr\/bqaa108"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.617089"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.31138\/mjr.28.2.64"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-021-00526-x"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3302036"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4515"}],"container-title":["Tropical Medicine &amp; International Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tmi.13947","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T20:16:38Z","timestamp":1705436198000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tmi.13947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,20]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1111\/tmi.13947"],"URL":"https:\/\/doi.org\/10.1111\/tmi.13947","archive":["Portico"],"relation":{},"ISSN":["1360-2276","1365-3156"],"issn-type":[{"value":"1360-2276","type":"print"},{"value":"1365-3156","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,20]]},"assertion":[{"value":"2023-11-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}