{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T04:54:36Z","timestamp":1785128076389,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T00:00:00Z","timestamp":1738454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Classic vector control tools do not sustainably reduce <jats:italic>Aedes<\/jats:italic> populations or prevent the surge of arboviruses. The sterile insect technique (SIT) by irradiation relies on mass\u2010rearing and release of male insects that will not produce viable offspring. It has been successfully integrated into controlling agricultural and livestock pests. Experiments are conducted to determine the effectiveness of the approach for suppressing <jats:italic>Aedes aegypti<\/jats:italic> and curbing dengue transmission. Detailed implementation cycle costs have not been reported yet.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To detail the costs of producing and releasing male <jats:italic>A. aegypti<\/jats:italic> mosquitoes sterilised by irradiation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We carried out a cost analysis during a SIT pilot trial in Havana. We took a provider perspective and used microcosting. From the cost function, we subsequently calculated costs for base case variations in production volume and mosquito release rate per hectare.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The setup expenses to establish the capacity to produce and release 450,000 mosquitoes weekly amounted to 155,452.00 and 2456.40\u2009USD in capital means and training, respectively. The average number of sterile mosquitoes released per hectare per week during the trial was 1500, utilising 17% of the installed capacity. Including capital depreciation, the average cost per 10,000 sterile male mosquitoes released was 110.12 USD. When producing at 85% capacity, this reduces nearly threefold, to 41.06\u2009USD. At that production level, releasing 500 or 4500 sterile male mosquitoes per hectare costs on average 2.70 or 16.54\u2009USD per hectare covered. In densely populated areas with 500 inhabitants per hectare, this corresponds to 0.28 or 1.72\u2009USD per inhabitant per year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our cost estimates for SIT by irradiation are within the range of estimates reported for alternative mass\u2010rearing and release methods to control <jats:italic>Aedes<\/jats:italic> populations, and the approach appears competitive with insecticide\u2010based interventions. The cost\u2010effectiveness in different contexts remains to be investigated.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.14086","type":"journal-article","created":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T02:00:13Z","timestamp":1738548013000},"page":"210-218","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The cost of the production and release of male <i>Aedes aegypti<\/i> mosquitoes sterilised by irradiation"],"prefix":"10.1111","volume":"30","author":[{"given":"A.","family":"Baly","sequence":"first","affiliation":[{"name":"Departments of Epidemiology and Vector Control Institute of Tropical Medicine Pedro Kouri  Havana Cuba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Gato","sequence":"additional","affiliation":[{"name":"Departments of Epidemiology and Vector Control Institute of Tropical Medicine Pedro Kouri  Havana Cuba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Garcia","sequence":"additional","affiliation":[{"name":"Municipal Centre of Epidemiology and Microbiology  Havana Cuba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Departments of Epidemiology and Vector Control Institute of Tropical Medicine Pedro Kouri  Havana Cuba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Van der Stuyft","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary care, Faculty of Medicine and Health Sciences Ghent University  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,2]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"WHO.Global Arbovirus Initiative: preparing for the next pandemic by tackling mosquito\u2010borne viruses with epidemic and pandemic potential [Internet].2024[cited 2024 Aug 5]. 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