{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:43:37Z","timestamp":1792428217003,"version":"4.5.0"},"reference-count":46,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T00:00:00Z","timestamp":1741305600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Strongyloides stercoralis<\/jats:italic> is a neglected soil\u2010transmitted helminth endemic in tropical and subtropical regions. This study aimed to determine the prevalence, risk factors, and spatial distribution of <jats:italic>S. stercoralis<\/jats:italic> infection in rural villages of Khon Kaen Province, Northeastern Thailand.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional survey was conducted among 260 participants from 201 households across five randomly selected villages. Stool samples were analysed using agar plate culture and formalin\u2010ethyl acetate concentration techniques, and soil samples were assessed for <jats:italic>S. stercoralis<\/jats:italic> DNA by PCR and physicochemical properties including pH, porosity, bulk density, moisture, organic matter, and nitrate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of <jats:italic>S. stercoralis<\/jats:italic> infection was 16.15%, with agar plate culture detecting 41 cases (15.77%) compared to 12 cases (4.62%) by formalin\u2010ethyl acetate concentration techniques. The highest prevalence was observed in Norng Thungmon village (31.80%). Risk factors included male gender, older age, being a head of household, living in homes with earthen floors, walking barefoot, and proximity to water sources. Soil samples from 169 households revealed an <jats:italic>S. stercoralis<\/jats:italic> detection rate of 8.3% via PCR. Positive soil samples were predominantly from Norng Huachang and Don Du villages. Spatial analysis identified significant clustering of infections within high\u2010risk areas. Soil physicochemical properties, including pH, moisture, and organic matter, were measured, though no significant correlations were found with infection rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In conclusion, <jats:italic>S. stercoralis<\/jats:italic> remains a significant health concern but is neglected in rural Khon Kaen, with identifiable human and environmental risk factors. Enhanced health education, improved sanitation, and targeted interventions are essential for reducing transmission in endemic areas.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.14100","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T21:20:38Z","timestamp":1741728038000},"page":"393-403","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Geospatial distribution and risk factors of <i>Strongyloides stercoralis<\/i> in rural communities of Northeast Thailand"],"prefix":"10.1111","volume":"30","author":[{"given":"Chivorn","family":"Leang","sequence":"first","affiliation":[{"name":"Tropical Disease Research Center, Faculty of Medicine Khon Kaen University  Khon Kaen Thailand"},{"name":"Department of Tropical Medicine, Faculty of Medicine Khon Kaen University  Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apiporn","family":"Suwannatrai","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Faculty of Medicine Khon Kaen University  Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sutas","family":"Suttiprapa","sequence":"additional","affiliation":[{"name":"Tropical Disease Research Center, Faculty of Medicine Khon Kaen University  Khon Kaen Thailand"},{"name":"Department of Tropical Medicine, Faculty of Medicine Khon Kaen University  Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thewarach","family":"Laha","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Faculty of Medicine Khon Kaen University  Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8899-5919","authenticated-orcid":false,"given":"Banchob","family":"Sripa","sequence":"additional","affiliation":[{"name":"Tropical Disease Research Center, Faculty of Medicine Khon Kaen University  Khon Kaen Thailand"},{"name":"Department of Tropical Medicine, Faculty of Medicine Khon Kaen University  Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,7]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"WHO guideline on preventive chemotherapy for public health control of strongyloidiasis.WHO Guidelines Approved by the Guidelines Review Committee. 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