{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:25:01Z","timestamp":1787163901562,"version":"build-2736575974"},"reference-count":79,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T00:00:00Z","timestamp":1747699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The coronavirus disease\u201019 (COVID\u201019) pandemic has affected global health, influencing the prevalence of different respiratory pathogens. The aim of this study is to evaluate the distribution of agents causing acute respiratory infections in children under 5\u2009years old before and after the COVID\u201019 pandemic in Praia, Cabo Verde, and to describe associated clinical variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Conducted at the University Hospital Dr. Agostinho Neto, this study replicated methods from a previous work from 2019 (Correia et al. 2021). Nasopharyngeal samples were analysed using FilmArray\u00ae Respiratory Panel 2.1 (BioFire) to identify agents of acute respiratory infections. Molecular identification of human respiratory syncytial virus subtypes was performed using a real\u2010time duplex reverse transcription polymerase chain reaction. Statistical analysis was performed using IBM SPSS version 29 and R 3.5.1 software.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In 2022, 86.5% (83\/96) of nasopharyngeal samples were positive for at least one pathogen. Human rhinovirus\/human enterovirus was the most frequent agent, followed by human respiratory syncytial virus, adenovirus and severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102). Co\u2010infections were observed in 43.3% of positive cases. Infection rates were significantly higher in children under 1\u2009year of age, particularly for SARS\u2010CoV\u20102 and human respiratory syncytial virus. Seasonal variations were observed, with human respiratory syncytial virus predominating in November, SARS\u2010CoV\u20102 in January and human parainfluenza virus\u20104 in May. Molecular analysis of human respiratory syncytial virus revealed a shift in subtype prevalence, with both human respiratory syncytial virus\u2010A and \u2010B co\u2010circulating in the pre\u2010pandemic period, whereas only human respiratory syncytial virus\u2010B was detected in the post\u2010pandemic period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our data indicate changes in the distribution of respiratory viruses in the post\u2010pandemic period compared to pre\u2010pandemic period. The high prevalence of co\u2010infections highlights the complexity of acute respiratory infection aetiology, emphasising the need for enhanced respiratory virus surveillance systems in Cabo Verde. Identifying seasonal trends and risk factors can contribute to targeted interventions and improved public health strategies to mitigate the burden of acute respiratory infections in young children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/tmi.14125","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T06:44:14Z","timestamp":1747723454000},"page":"694-703","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Epidemiological and clinical profile of viral respiratory infections in children under 5\u2009years at pre\u2010 and post\u2010\n                    <scp>COVID<\/scp>\n                    \u201019 era in Praia, Cabo Verde"],"prefix":"10.1111","volume":"30","author":[{"given":"Wilson","family":"Correia","sequence":"first","affiliation":[{"name":"Instituto Universitario de Enfermedades Tropicales y Salud P\u00fablica de Canarias Universidad de La Laguna  La Laguna Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Dorta\u2010Guerra","sequence":"additional","affiliation":[{"name":"Instituto Universitario de Enfermedades Tropicales y Salud P\u00fablica de Canarias Universidad de La Laguna  La Laguna Spain"},{"name":"Departamento de Matem\u00e1ticas, Estad\u00edstica e Investigaci\u00f3n Operativa, Facultad de Ciencias Universidad de La Laguna  La Laguna Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitza","family":"Sanches","sequence":"additional","affiliation":[{"name":"Hospital Universit\u00e1rio Dr. Agostinho Neto Ministry of Health and Social Security of Cabo Verde  Praia Cabo Verde"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basilio","family":"Valladares","sequence":"additional","affiliation":[{"name":"Instituto Universitario de Enfermedades Tropicales y Salud P\u00fablica de Canarias Universidad de La Laguna  La Laguna Spain"},{"name":"Departamento de Obstetricia y Ginecolog\u00eda, Pediatr\u00eda, Medicina Preventiva y Salud P\u00fablica, Toxicolog\u00eda, Medicina Legal y Forense y Parasitolog\u00eda Universidad de La Laguna  La Laguna Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel In\u00eas M.","family":"de Pina\u2010Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias e Tecnologia Universidade de Cabo Verde  Praia Cabo Verde"},{"name":"oNe hEalth research cenTer de Cabo Verde \u2013 NEST\u2010CV Universidade de Cabo Verde  Praia Cabo Verde"},{"name":"Global Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA\u2010REAL, Instituto de Higiene e Medicina Tropical, IHMT Universidade NOVA de Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1126-993X","authenticated-orcid":false,"given":"Emma","family":"Carmelo","sequence":"additional","affiliation":[{"name":"Instituto Universitario de Enfermedades Tropicales y Salud P\u00fablica de Canarias Universidad de La Laguna  La Laguna Spain"},{"name":"Departamento de Obstetricia y Ginecolog\u00eda, Pediatr\u00eda, Medicina Preventiva y Salud P\u00fablica, Toxicolog\u00eda, Medicina Legal y Forense y Parasitolog\u00eda Universidad de La Laguna  La Laguna Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(24)00176-2"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)00138-7"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25582"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-023-05698-6"},{"key":"e_1_2_10_6_1","unstructured":"Minist\u00e9rio da Sa\u00fade e de Seguran\u00e7a Social de Cabo verde.COVID 19 \u2013 Corona Virus [Internet].2024[cited 2024 Sep 27]. 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