{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T16:24:42Z","timestamp":1782059082405,"version":"3.54.5"},"reference-count":37,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T00:00:00Z","timestamp":1755043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","award":["APQ\u201002901\u201024"],"award-info":[{"award-number":["APQ\u201002901\u201024"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Tuberculosis, although curable, presents challenges related to treatment adherence, which compromises treatment effectiveness. Individual, social and structural barriers interfere with patients' ability to properly follow the therapeutic regimen, thereby impacting treatment outcomes. Given the limitations of the conventional healthcare model, which relies primarily on in\u2010person consultations and standard treatment protocols without additional adherence support technologies, new approaches have been explored to improve patient outcomes. This study seeks to identify effective communication approaches in this context.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To identify the most effective communication strategies to optimise treatment adherence and improve therapeutic success in patients diagnosed with tuberculosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic review with meta\u2010analysis was conducted. We included studies available in the MEDLINE (via PubMed), EMBASE and SCOPUS databases, with publication dates between January 2005 and December 2024. The primary outcomes were adherence to and success in tuberculosis treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This systematic review included 17 studies on tuberculosis treatment adherence. Of these, 12 were included in the meta\u2010analysis for adherence and 8 for treatment success. The most effective strategies for adherence were community education (2 studies; RR: 0.25, 95% CI: 0.11\u20130.56) and video observed therapy (VDOT) (2 studies; RR: 0.29, 95% CI: 0.21\u20130.40). The combination of electronic devices with SMS also showed positive results (3 studies; RR: 0.53, 95% CI: 0.37\u20130.77). SMS alone (5 studies) and electronic devices alone (3 studies) were not effective. For treatment success, only the combination of electronic devices with SMS (RR: 0.31, 95% CI: 0.17\u20130.55) and community education (RR: 0.51, 95% CI: 0.40\u20130.64) were effective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The combination of electronic devices with SMS and community education is an effective strategy for improving adherence and therapeutic success in tuberculosis treatment. Isolated interventions with SMS or electronic technologies did not show significant results. Adapting approaches to local realities is crucial for optimising outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tmi.70013","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:34:32Z","timestamp":1755131672000},"page":"1053-1068","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effects of Communication Strategies on Treatment Adherence and Success in Tuberculosis: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-7743-6148","authenticated-orcid":false,"given":"Omar Oliveira","family":"Meira","sequence":"first","affiliation":[{"name":"Graduate Program in Health Sciences, Department of Medicine and Nursing Federal University of Vi\u00e7osa  Vi\u00e7osa Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4713-6671","authenticated-orcid":false,"given":"Luiz Gustavo Ribeiro","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Medicine and Nursing Federal University of Vi\u00e7osa  Vi\u00e7osa Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4894-1367","authenticated-orcid":false,"given":"Raquel Fonseca","family":"Sales","sequence":"additional","affiliation":[{"name":"Department of Medicine and Nursing Federal University of Vi\u00e7osa  Vi\u00e7osa Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2976-881X","authenticated-orcid":false,"given":"Renata Maria","family":"Colodette","sequence":"additional","affiliation":[{"name":"Dentistry Course Health Sciences Center, Vi\u00e7osa University Center (UNIVI\u00c7OSA)  Vi\u00e7osa Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7936-3343","authenticated-orcid":false,"given":"Lucas Borges Gomes Ferreira","family":"Pinto","sequence":"additional","affiliation":[{"name":"Department of Medicine and Nursing Federal University of Vi\u00e7osa  Vi\u00e7osa Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4451-0611","authenticated-orcid":false,"given":"Emily de Souza","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Graduate Program in Nutrition Science, Department of Health Nutrition Federal University of Vi\u00e7osa  Vi\u00e7osa Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5331-9734","authenticated-orcid":false,"given":"Ros\u00e2ngela Minardi Mitre","family":"Cotta","sequence":"additional","affiliation":[{"name":"Graduate Program in Nutrition Science, Department of Health Nutrition Federal University of Vi\u00e7osa  Vi\u00e7osa Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6606-4942","authenticated-orcid":false,"given":"Tiago Ricardo","family":"Moreira","sequence":"additional","affiliation":[{"name":"Graduate Program in Health Sciences, Department of Medicine and Nursing Federal University of Vi\u00e7osa  Vi\u00e7osa Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,13]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Global Tuberculosis Report 2024","author":"World Health Organization","year":"2024"},{"key":"e_1_2_10_3_1","unstructured":"Organiza\u00e7\u00e3o Pan\u2010Americana da Sa\u00fade \u201cTuberculose Ressurge Como a Principal Causa de Morte Por Doen\u00e7a Infecciosa \u201d(2024) https:\/\/www.paho.org\/pt\/noticias\/1\u201011\u20102024\u2010tuberculose\u2010ressurge\u2010como\u2010principal\u2010causa\u2010morte\u2010por\u2010doenca\u2010infecciosa."},{"key":"e_1_2_10_4_1","unstructured":"Organiza\u00e7\u00e3o Mundial da Sa\u00fade \u201cTuberculose \u201d(2025) https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/tuberculosis."},{"key":"e_1_2_10_5_1","volume-title":"Global Tuberculosis Report 2022","author":"World Health Organization","year":"2022"},{"issue":"1","key":"e_1_2_10_6_1","first-page":"21","article-title":"Tratamento da Tuberculose","volume":"16","author":"Campos H. S.","year":"2007","journal-title":"Pulm\u00e3o RJ"},{"key":"e_1_2_10_7_1","volume-title":"Global Tuberculosis Report 2021","author":"World Health Organization","year":"2021"},{"key":"e_1_2_10_8_1","volume-title":"Manual de Recomenda\u00e7\u00f5es Para o Controle da Tuberculose no Brasil","author":"Brasil. Minist\u00e9rio da Sa\u00fade","year":"2019"},{"key":"e_1_2_10_9_1","volume-title":"Recomenda\u00e7\u00f5es Para o Controle da Tuberculose: Guia R\u00e1pido Para Profissionais de Sa\u00fade","author":"BRASIL. Minist\u00e9rio da Sa\u00fade","year":"2021"},{"key":"e_1_2_10_10_1","volume-title":"International Standards for Tuberculosis Care","author":"TB CARE I","year":"2014"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0040238"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063\u2010020\u201004324\u2010z"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.7309\/jmtm.5.2.3"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.33194\/rper.2018.v1.n1.07.4391"},{"key":"e_1_2_10_15_1","unstructured":"Organiza\u00e7\u00e3o Pan\u2010Americana de Sa\u00fade; Organiza\u00e7\u00e3o Mundial de Sa\u00fade \u201cAumenta a Morbimortalidade Por Tuberculose Durante a Pandemia de COVID\u201019 \u201d(2022) https:\/\/www.who.int\/news\/item\/27\u201010\u20102022\u2010tuberculosis\u2010deaths\u2010and\u2010disease\u2010increase\u2010during\u2010the\u2010covid\u201019\u2010pandemic."},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.4102\/curationis.v39i1.1629"},{"key":"e_1_2_10_17_1","unstructured":"G. A.Wells B.Shea D.O'connell et\u00a0al. \u201cThe Newcastle\u2010Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta\u2010Analyses \u201dacesso em 21 jun. 2025 http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp."},{"key":"e_1_2_10_18_1","volume-title":"Review Manager (RevMan) [Computer program]. Version 5.4","year":"2020"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1482"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d4002"},{"key":"e_1_2_10_22_1","unstructured":"Joanna Briggs Institute \u201cCritical Appraisal Tools \u201dacesso em 1 abr. 2024 https:\/\/jbi.global\/critical\u2010appraisal\u2010tools."},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.21.0373"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002891"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.4.380"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmacy9020086"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00493\u20102020"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16030412"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889\u2010018\u20105502\u2010x"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0162944"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/jjns.12134"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001876"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2023.923319"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.22.0500"},{"key":"e_1_2_10_36_1","volume-title":"Implementing the End TB Strategy: The Essentials, 2022 Update","author":"World Health Organization","year":"2022"},{"key":"e_1_2_10_37_1","unstructured":"C. S.Prado J. M.Ten\u00f3rio E. E. S.Ruiz C. L. F.Ortolani andI. T.Pisa \u201cImpacto da Utiliza\u00e7\u00e3o de Mensagens do Tipo SMS (Short Message Service) Como Lembrete na Ades\u00e3o ao Tratamento de Sa\u00fade: Revis\u00e3o Sistem\u00e1tica da Literatura \u201d(2012) https:\/\/www.academia.edu\/50913688\/Impacto_da_utiliza%C3%A7%C3%A3o_de_mensagens_do_tipo_SMS_Short_Message_Service_como_lembrete_na_ades%C3%A3o_ao_tratamento_de_sa%C3%BAde_revis%C3%A3o_sistem%C3%A1tica_da_literatura."},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0088166"}],"container-title":["Tropical Medicine &amp; International Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tmi.70013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T07:05:33Z","timestamp":1759820733000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tmi.70013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,13]]},"references-count":37,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1111\/tmi.70013"],"URL":"https:\/\/doi.org\/10.1111\/tmi.70013","archive":["Portico"],"relation":{},"ISSN":["1360-2276","1365-3156"],"issn-type":[{"value":"1360-2276","type":"print"},{"value":"1365-3156","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,13]]},"assertion":[{"value":"2025-05-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}