{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T04:52:37Z","timestamp":1777956757003,"version":"3.51.4"},"reference-count":65,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:00:00Z","timestamp":1771545600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:00:00Z","timestamp":1771545600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Gonorrhoea remains a leading sexually transmitted infection worldwide, with an estimated 82 million new cases being reported annually. In Kenya, epidemiological and antimicrobial resistance data are fragmented and under\u2010represent high\u2010risk populations, hampering targeted interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To estimate the pooled prevalence of\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Neisseria gonorrhoeae<\/jats:italic>\n                      <\/jats:styled-content>\n                      and assess patterns of antimicrobial resistance in Kenya between 2019 and 2024.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>\n                      We searched PubMed, Google Scholar, OpenAlex and Research4Life following PRISMA guidelines, yielding 1116 records. Two reviewers independently screened studies against predefined inclusion criteria. Prevalence and resistance data were extracted, and a random\u2010effects meta\u2010analysis was performed to compute pooled estimates with 95% confidence intervals. Heterogeneity among studies was assessed using the I\n                      <jats:sup>2<\/jats:sup>\n                      statistic.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eleven studies comprising 5170 participants met inclusion criteria. The pooled prevalence of\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>N. gonorrhoeae<\/jats:italic>\n                      <\/jats:styled-content>\n                      was 22.5% (95% CI: 17.2\u201327.8). Key risk factors included sex work, low educational attainment and multiple sexual partners. Resistance rates were highest for tetracycline (98.0%), ciprofloxacin (96.7%) and penicillin (94.7%) and lowest for azithromycin (2.0%), cefixime (2.6%) and ceftriaxone (1.3%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>N. gonorrhoeae<\/jats:italic>\n                      <\/jats:styled-content>\n                      poses an urgent public health threat in Kenya. Strengthening surveillance, expanding access to reliable diagnostics and enforcing antibiotic stewardship are critical. Exploration of alternative therapies including phage therapy, alongside accelerated vaccine research, will be essential for sustainable disease control.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/tmi.70094","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T09:45:17Z","timestamp":1771580717000},"page":"623-633","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>\n                      <i>Neisseria gonorrhoeae<\/i>\n                    <\/scp>\n                    in Kenya: A Systematic Review and Meta\u2010Analysis of Prevalence, Resistance and Mitigation Strategies"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3518-1142","authenticated-orcid":false,"given":"Samuel K.","family":"Ndegwa","sequence":"first","affiliation":[{"name":"Phage Hunters Training and Research Program  Nairobi Kenya"},{"name":"Center for Microbiology Research Kenya Medical Research Institute  Nairobi Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2929-341X","authenticated-orcid":false,"given":"Ivy J.","family":"Mutai","sequence":"additional","affiliation":[{"name":"Phage Hunters Training and Research Program  Nairobi Kenya"},{"name":"Antimicrobial Resistance and Bacteriophage Biology Section, Department of Reproductive Health &amp; 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